【Animal Modeling】-Analysis of basic physiological and biochemical indicators of male and female FMMU albino guinea pigs

To measure and compare the blood indexes, heart rate, common carotid arterial pressure, ventricular pressure and organ parameters of female and male common-grade FMMU albino guinea pigs...

2022-07-26

【Animal Modeling】-Effect of two-color coreopsis alcohol extract on intestinal flora of type 2 diabetic mice

To investigate the possible link between the alcoholic extract of coreopsis bicolor, intestinal flora and type 2 diabetes mellitus (T2DM)...

2022-07-25

【Animal Modeling】-Effect of plantar shock stress duration on anxiety-like behavior in rats

To observe the effects of plantar shock stress duration on the elevated plus maze and anxiety-like behaviors in the opening test in rats...

2022-07-25

【Animal Modeling】-Effect of Atractylodes Rhizoma Extract on gastric mucosa and gastrointestinal immune function in rats with spleen deficiency syndrome

To investigate the protective effect of Atractylodes Rhizoma extract on gastric mucosa and its effect on gastrointestinal immune function in spleen deficiency model rats, and to clarify the mechanism of ERA\'s intervention in spleen deficiency syndro...

2022-07-25

【Animal Modeling】-Effect of hydrogen sulfide on myocardial fibrosis and expression of MAPK1/3 and MMP-8 in diabetic rats

To investigate the effect of gas signal molecule hydrogen sulfide (H2S) on myocardial fibrosis and protein expression of MAPK1/3 and MMP-8 in diabetic rats...

2022-07-25

【Animal Modeling】-Minocycline inhibits the hyperpolarization-activated current of glial neurons in the dorsal horn of rat spinal cord

To study the effect of minocycline on the hyperpolarization-activated current (Ih) of colloidal (SG) neurons in the spinal dorsal horn of rats...

2022-07-25

【Animal modeling】-Protective effect of emulsified fluorocarbon combined with ligustrazine on pulmonary ischemia-reperfusion injury in rats

To investigate the effect and mechanism of emulsified fluorocarbon combined with ligustrazine on pulmonary ischemia-reperfusion injury...

2022-07-25

【Animal Model】-Inhibitory effect of chloroquine on airway hyperresponsiveness in asthmatic mice

To investigate the effect of chloroquine on airway hyperresponsiveness in asthmatic mice and its possible mechanism...

2022-07-25

【Animal Modeling】-Effect of repetitive hypoxic preconditioning on liver injury induced by renal ischemia-reperfusion in rats

To investigate the effect of repetitive hypoxic preconditioning (RHP) on liver injury induced by renal ischemia-reperfusion injury (IRI) in rats and to preliminarily explore its mechanism...

2022-07-25

【Animal modeling】-The role of KA1 subreceptors in the death of hippocampal neurons induced by endoplasmic reticulum stress

To explore the role of up-regulated expression of KA1 sub-receptors in the death of hippocampal neurons induced by endoplasmic reticulum stress...

2022-07-25

【Animal Modeling】-Lentivirus-mediated shRNA targeting survivin gene inhibits the growth of endometrium in the abdominal cavity of nude mice

To study the effect of lentivirus-mediated survivin gene-specific short hairpin RNA (shRNA) on the growth of human endometrium in the peritoneal cavity of nude mice...

2022-07-25

【Animal Modeling】-Effect of alcohol exposure during pregnancy on basal rhythmic respiratory discharges in the medulla oblongata of neonatal rats

To investigate the effect of alcohol exposure during pregnancy on the basic rhythmic respiratory discharge in medullary bulb slices of offspring neonatal rats...

2022-07-25

【Animal Modeling】-miR-20b inhibits airway inflammation in asthmatic mice

To investigate the effect of miR-20b on airway inflammation in asthmatic mice...

2022-07-25

【Animal Modeling】-Regulatory T cell therapy for experimental mouse polymyositis and its mechanism

To investigate the therapeutic value and mechanism of CD4+ CD25+ Foxp3+ Treg cells in experimental autoimmune myositis (EAM) mice...

2022-07-25

【Animal modeling】-The treatment and mechanism of hemin on gestational hypertensive rats

To preliminarily explore the therapeutic effect and possible regulatory mechanism of heme oxygenase inducer hemin (Hemin) in rats with pregnancy-induced hypertension (HDCP)...

2022-07-25

【Animal modeling】- Oral human alpha interferon transforms Bifidobacterium to promote the proliferation and maturation of mouse lymphocytes

To investigate the regulatory effect of human alpha interferon (IFN-α) gene on the immune function of mice after oral administration of Bifidobacterium transformed...

2022-07-25