【Animal modeling】-Effect of Bcl-2 inhibitor on astragalus injection on reducing the apoptosis of hippocampal neurons in rats with hypoxia and hypoglycemia/reoxygenation and reglycemia

To investigate the effect of astragalus injection (AI) on the apoptosis of hippocampal neurons in hypoxia-hypoglycemia/reoxygenation and reglycemia (H/R) rats under the action of Bcl-2 inhibitor (TW-37)...

2022-07-20

【Animal modeling】-The role of CaN-NFATc3 pathway in restenosis after balloon dilation of abdominal aorta in rats

To study the role of calcineurin (CaN) and its downstream activated T cell nuclear factor (NFATc3) in restenosis after balloon dilatation, and to provide a new theoretical basis for the prevention and treatment of vascular restenosis...

2022-07-20

【Animal Modeling】-Study on the synergistic analgesic effect of choline and parecoxib sodium and its mechanism through mouse experiments

To investigate the interaction between choline and parecoxib sodium in analgesia and to conduct a preliminary study on its mechanism...

2022-07-20

【Animal modeling】-Experimental study on the differentiation of bone marrow mesenchymal stem cells into cardiomyocyte-like cells induced by Jiawei Danshen Decoction in vitro

To investigate the experimental study on the differentiation of bone marrow mesenchymal stem cells into cardiomyocyte-like cells induced by Modified Danshen Decoction in vitro...

2022-07-20

【Animal Modeling】-Effects of benzene pollution on liver and kidney function and blood nucleotide levels in rats

To explore the effect of benzene on liver and kidney function and blood nucleotide levels in Wistar rats...

2022-07-20

【Animal modeling】-The effect of long-term consumption of Polygonum multiflorum on the hematopoietic system of mice

To investigate the changes of mouse hematopoietic system after long-term consumption of Polygonum multiflorum...

2022-07-20

【Animal modeling】-Protective effect of ginseng coenzyme Q10 sunscreen on UV-injured mice

To study the protective effect of ginseng coenzyme Q10 sunscreen on UV-injured mice...

2022-07-20

【Animal Modeling】-Preliminary study on the mechanism of hypoxic preconditioning reducing the susceptibility to epilepsy and its brain protective effect in rats

To preliminarily investigate the effect of intermittent hypoxic preconditioning on epileptic seizures in rats induced by lithium chloride and pilocarpine and its brain protective mechanism...

2022-07-20

【Animal Modeling】-A comparative study of two puncture routes for hepatic artery intubation in rabbits

To explore the route and method of hepatic artery cannulation in experimental rabbits...

2022-07-20

【Animal modeling】-The role of stromal cell-derived factor-1 and chemokine receptor 4 in the rejection of rat corneal transplantation

To investigate the expressions of stromal cell-derived factor-1 (SDF-1) and stromal cell-derived factor-1 (CXCR4) in rat corneal tissue and their roles in immune rejection after keratoplasty...

2022-07-20

【Animal modeling】-Effect of Lycium barbarum polysaccharide on tumor growth and metastasis in spontaneous breast cancer MMTV-PyMT mice

To investigate the effect of Lycium barbarum polysaccharide on the growth and metastasis of breast cancer using MMTV-PyMT mice as a breast cancer model...

2022-07-20

【Animal modeling】-Distribution and differential expression of Hba-α protein in hatched blastocysts and dormant embryos of mice before and after programmed freezing

To explore the distribution and differential expression of Hba-α protein in hatched blastocysts and dormant embryos of mice before and after freezing by means of programmed freezing, so as to provide a theoretical basis for the future development and...

2022-07-20

【Animal modeling】-The effect of targeted inhibition of macrophage Act1 expression on ulcerative colitis

To investigate the role of macrophage NF-κB activating factor 1 in inflammatory bowel disease...

2022-07-20

【Animal Modeling】-Effects of heat exposure in the second trimester on the intrauterine development of rat offspring and the expression of HSP70, Bax and Bcl-2 in the placenta

To investigate the effect of heat exposure in the second trimester on the intrauterine growth and development of rat placenta and offspring...

2022-07-20

【Animal Modeling】-Study on the anxiety-like behavior of rats induced by different stress methods at different time points

To compare the biological characteristics of several different stress methods to establish an anxiety rat model from different time points, and to provide an experimental basis for finding the most suitable modeling method...

2022-07-20

【Animal Modeling】-Study on the analgesic effect of oxysophocarpine on inflammatory pain in mice

To study the effect of oxysophocarpine on xylene and carrageenan-induced inflammatory pain in mice to explore its possible mechanism...

2022-07-20