
To explore the therapeutic effect of rapamycin on primary sclerosing cholangitis (PSC) in mice induced by 3,5-diethoxycarbonyl 1,4-dihydrocollidine (DDC), and explore its potential mechanism...
2022-01-04
To study the improvement of acupuncture on the symptoms of insomnia rats and its influence on spontaneous activities, and to explore its possible mechanism...
2022-01-04
To study the inhibitory effect of cytomegalovirus (CMV) on the immune response of mice implanted with polymethyl methacrylate (PMMA)....
2022-01-04
To evaluate the effects of cobalt, chromium and molybdenum metal (trade name: Vitalin), zirconium dioxide porcelain, and polymethyl methacrylate resin three kinds of dental grinding dust on lung tissue damage in rats...
2021-12-31
\\\\\\\"One injection should last at least four months.\\\\\\\" A research team in the United States has developed a new drug to control blood sugar and has achieved success in animal studies....
2021-12-31![[Animal Modeling]-Effect of Naoshuantong Capsules on the Expression of Inflammatory Factors in ApoE-/- Mice](/./uploads/images/default/default.png)
To observe the effects of Naoshuantong Capsules on the inflammation-related factors interleukin-1β (interleukin-1 beta, IL-1β), interleukin-6 (interleukin-6, IL-6) and tumors in ApoE-/- atherosclerosis mouse model. Necrosis factor (tumor necrosis fac...
2021-12-31
To explore the effects of oxidative stress on the proliferation, apoptosis, collagen synthesis and expression of inflammatory factors in uterine ligament fibroblasts and possible mechanisms...
2021-12-31![[Animal Modeling]-Changes and Significance of Arterial Blood Gas Analysis Indexes in Rats with Chronic Hypoxic Pulmonary Hypertension](/./uploads/images/default/default.png)
To investigate the changes and significance of arterial blood gas analysis indexes in a rat model of hypoxic pulmonary hypertension induced by chronic hypoxia...
2021-12-31
To explore the protective effect and mechanism of estrogen on oxidative stress injury of mouse osteoblast MC3T3-E1...
2021-12-31![[Animal modeling]-Increased serotonin can prevent mice from becoming addicted to cocaine](/./uploads/images/default/default.png)
Researchers report that elevated serotonin levels can prevent mice from compulsive seeking and addiction to cocaine...
2021-12-31![[Animal Modeling]-Emphysema animal model](/./uploads/images/default/default.png)
The solution is placed in a sealed reproductive method test guinea pig (male or female) ventilated isolation bag, then exposed to tobacco smoke, daily (10 rows/time, once/day, 5D)/1 week, 1, 3, 6, and 12 Month, lung histopathology and lung function t...
2021-12-31
Objective To study the effects of Oct4 and Cdx2 knockdown on the expression of genes related to the differentiation of bovine ICM and TE, and to explain the role of Oct4 and Cdx2 in the early development of bovine embryos...
2021-12-31
Objective To explore the effect of alprostadil (PGE1) on liver function in rats with fulminant hepatic failure (FHF), and to explore its effect on eukaryotic translation initiation factor 2α (eIF2α) / activating transcription factor 4 (ATF4) / C/ EB...
2021-12-31![[Animal Modeling]-Ke Shan Ting regulates skin inflammation and autophagy in mice with psoriasis by inhibiting C5a/C5aR1 pathway](/./uploads/images/default/default.png)
This study intends to use imiquimod (IMQ) mouse psoriasis model to explore the regulation effect of Cosentyx on skin inflammation and autophagy in psoriasis mice through the C5a / C5aR1 pathway...
2021-12-31
Objective To explore the effects of salidroside (Sal) on the nuclear transcription factor E2 related factor 2 / Kelch-like epichlorohydrin related protein 1 (Nrf2 / Keap1) signaling pathway and wound healing in rats with diabetic foot ulcer (DFU)...
2021-12-31
Establish an animal model of cynomolgus muscle atrophy, and use the method of restricting the movement of the lower limbs to establish a model evaluation method?...
2021-12-30