
Construction of miR-223 knockout mice using dual sgRNAs...
2021-11-12![[Animal Modeling]-Screening EV71 pathogenicity-related genes through genetic diversity mice](/./uploads/images/default/default.png)
Screen the pathogenicity-related genes of enterovirus 71 through genetic diversity mouse resources, deeply understand the pathogenic mechanism of the virus, and provide the basis for clinical diagnosis, treatment and prognosis...
2021-11-12![[Animal modeling]-Pathological changes of bone, liver, kidney and brain tissue in fluorosis rats](/./uploads/images/default/default.png)
To study the effect of sodium fluoride on the pathology of rat bone, brain, liver and kidney tissues...
2021-11-12
By comparing the effects of three conventional animal anesthetics on the ECG of C57BL/6 mice, explore the anesthetics that have less interference on the ECG of mice...
2021-11-12![[Animal Modeling]-Phenotype and Pathological Observation of SD Rats with Leptin Receptor Knockout](/./uploads/images/default/default.png)
To observe the various parameters of the leptin receptor gene knockout rat model with obesity, metabolic syndrome and pre-diabetes characteristics established by CRISPR/Cas9 technology, and to provide a more ideal model for the molecular mechanism re...
2021-11-12
Reproductive method Inject 0.16% sodium selenite solution into the abdominal cavity of 12-day-old pups weighing about 25g, weighing 0.26ml/kg, rat cataract...
2021-11-11
To explore the effect of miR-20b on airway inflammation in asthmatic mice...
2021-11-11![[Animal Modeling]-Human-derived xenograft nude mouse model of prostate cancer](/./uploads/images/default/default.png)
How to establish a human-derived prostate cancer xenograft (PDX) model and evaluate the anti-tumor effects of various treatment options?...
2021-11-11
A research team in the United States developed a new drug to control blood sugar, and it was successful in animal experiments. The researchers said that the study involves a hormone that occurs naturally in the human brain, which is expected to help...
2021-11-11
To explore the effect of melittin intervention on the regulation of Th17/Treg balance and joint inflammation in a rat model of collagen-induced arthritis...
2021-11-11
To study the pathological changes of important brain areas in rats with post-traumatic stress disorder after compound stimulation...
2021-11-11
xplore whether simple ligation of the left portal vein can form stable portal hypertension and whether nitric oxide plays a corresponding role in it...
2021-11-11
Allograft vascular disease (AV) limits the function and long-term survival of transplanted organs. This is the most pressing global issue in the field of organ transplantation...
2021-11-11
Establish an experimental animal model of BALB/c mouse total hysterectomy, and explore and analyze the characteristics and formation mechanism of the model...
2021-11-11
How to establish a colon cancer liver metastasis model with high metastasis rate? Is the operation simple? Reliable results of experimental studies on the prevention and treatment of colon cancer metastasis?...
2021-11-11
Alcoholic liver disease (ALD) patients show a wide range of defects, from simple steatosis to steatohepatitis, fibrosis, cirrhosis and hepatocellular carcinoma...
2021-11-11