【Disease Animal Model】-Replication method of tumor model

There are many ways to replicate animal tumors, such as irradiating laboratory animals with radiation or intravenously or locally injecting radioisotopes; using various chemical carcinogens (alkylating agents, polycyclic aromatic hydrocarbons, aromat...

2022-11-08

【Animal modeling】-The effect of targeted inhibition of macrophage Act1 expression on ulcerative colitis

To investigate the role of macrophage NF-κB activating factor 1 in inflammatory bowel disease...

2022-11-08

【Animal Modeling】-miR-20b inhibits airway inflammation in asthmatic mice

To investigate the effect of miR-20b on airway inflammation in asthmatic mice...

2022-11-08

【Animal modeling】-C57BL/6J mouse frozen-thawed IVF prokaryotic embryos used for Cas9 microinjection

To explore the feasibility of using Cas9 injection in mice after in vitro fertilization freeze-thaw...

2022-11-08

【Animal Modeling】-Study on the analgesic effect of oxysophocarpine on inflammatory pain in mice

To study the effect of oxysophocarpine on xylene and carrageenan-induced inflammatory pain in mice to explore its possible mechanism...

2022-11-08

【Animal modeling】-Effect of sugar supplementation on the activation of adenosine monophosphate-activated protein kinase in the myocardium of acute exercise rats

To investigate the effect of sugar supplementation on the activation of AMPK in exercise myocardium by measuring the changes in myocardial adenosine monophosphate-activated protein kinase activity and glycogen content after acute exercise in rats...

2022-11-05

【Animal Modeling】-Determination and Analysis of Hematology and Serum Biochemical Indexes in African Green Monkeys

To detect the hematology and serum biochemical indexes of 50 healthy African green monkeys, and to analyze the hematology and serum biochemistry of African green monkeys of different genders and age groups (young group: 1-3 years old, adult group: 4-...

2022-11-05

【Animal Modeling】-Effect of Shenzhiling Oral Liquid on Early Hippocampal Synapse and Myelin Changes in App/Ps1 Double Transgenic Mice

To observe the early neuroprotective effect of Shenzhiling oral liquid on AD mice by observing the ultrastructure of myelin sheath and synapse in the CA1 region of the hippocampus and the special staining changes of myelin sheath in 3-month-old App/P...

2022-11-05

【Animal modeling】-Effect of maca combined with exercise therapy on renal mitochondrial respiratory chain enzyme activity and renal function in diabetic rats

To observe the effect of maca combined with exercise therapy on renal mitochondrial respiratory enzyme activity and renal function in diabetic rats...

2022-11-05

【Animal modeling】-Hydroxyethyl starch 40 sodium chloride injection allergic experimental study

To evaluate the allergic safety of hydroxyethyl starch 40 sodium chloride injection...

2022-11-05

【Animal Modeling】-Comparison of Different Methods of Inducing THP-1 Cell Differentiation

To optimize different methods to stimulate the directional differentiation of THP-1 cells into M1, M2 macrophages and DC cells, and lay the foundation for the study of three in vitro cell models of M1, M2 and DC...

2022-11-04

[Animal modeling] - Establishment and evaluation of an animal model of skin pruritus in guinea pigs

To optimize the dose of histamine and 4-aminopyridine (4-AP) by central composite design response plane method, in order to establish a new model of pruritus in guinea pigs...

2022-11-04

[Animal modeling] - Establishment of a functional dyspepsia model in rats with anxiety like gastric hypersensitivity induced by a new sequential stress method

To establish an anxiety like gastric hypersensitivity rat model by using a new sequential stress method...

2022-11-04

[Animal modeling] - Methodology review of experimental animal models of chronic obstructive pulmonary disease

Chronic obstructive pulmonary disease (COPD) is the main cause of incidence rate and mortality worldwide...

2022-11-04

[Animal modeling] - Establishment and evaluation of rat model of endometriosis with pelvic adhesion

To explore the establishment method and evaluation index of endometriosis pelvic adhesion rat model...

2022-11-04

[Animal modeling] - Establishment of a mouse model of IgA nephropathy induced by superantigen staphylococcal enterotoxin B

To establish a mouse model of IgA nephropathy and observe the biochemical and pathological characteristics of the model...

2022-11-04