[Animal modeling] - Establishment, identification and preliminary phenotype of oligodendrocyte conditionally knockout FGF9 gene mouse model

To establish oligodendrocyte specific knockout fibroblast growth factor 9 (FGF9) mouse model and further study the role of FGF9 in neural development...

2022-10-31

[Animal modeling] - Research progress in animal models of vascular cognitive impairment

Vascular cognitive impairment is one of the hot spots in medical research in recent years...

2022-10-31

[Animal model] - Preparation and evaluation of rat model of acute myocardial injury induced by different doses of isoproterenol

To study the effects of different doses of isoproterenol on cardiac function and pathomorphology in rats...

2022-10-31

[Animal modeling] - Analysis of thyroid function in rats with chronic intermittent hypoxia

Exploring the relationship between obstructive sleep apnea hypopnea syndrome and thyroid function through chronic intermittent hypoxia rat model...

2022-10-31

[Animal modeling] - Optimization of interstitial cystitis model in rats induced by intraperitoneal injection of cyclophosphamide

To explore the ideal dose of cyclophosphamide for establishing interstitial cystitis model in rats...

2022-10-31

[Animal model] - Preparation and evaluation of rat model of acute myocardial injury induced by different doses of isoproterenol

To study the effects of different doses of isoproterenol on cardiac function and pathomorphology in rats...

2022-10-31

[Animal modeling] - The role of GIPR signal transduction in adipose tissue of mouse model in insulin resistance and liver steatosis

To evaluate the role of GIP receptor (GIPR) signal transduction in insulin resistance and liver steatosis in mouse model adipose tissue by ultrasound...

2022-10-31

【Animal Modeling】-The synergistic effect of acupuncture on human amniotic mesenchymal cell transplantation in the treatment of osteoporosis in ovariectomized rats

To investigate the synergistic effect of acupuncture combined with human amniotic mesenchymal cell transplantation on ovariectomized osteoporosis...

2022-10-26

【Animal modeling】-The effect of targeted inhibition of macrophage Act1 expression on ulcerative colitis

To investigate the role of macrophage NF-κB activating factor 1 in inflammatory bowel disease...

2022-10-26

【Animal modeling】-Experimental study on puerarin alleviating radiation-induced acute intestinal mucosal injury in rats

To study the protective effect of puerarin on the intestinal mucosal injury of SD rats induced by radiation and its molecular mechanism...

2022-10-26

【Animal modeling】-Effect of Lycium barbarum polysaccharide on tumor growth and metastasis in spontaneous breast cancer MMTV-PyMT mice

To investigate the effect of Lycium barbarum polysaccharide on the growth and metastasis of breast cancer using MMTV-PyMT mice as a breast cancer model...

2022-10-26

【Animal modeling】-Recombinant lentivirus-mediated LXRα RNA interference improves the function of rat fatty liver donor liver transplantation

To investigate the effect and mechanism of LXRα RNA interference (RNAi) in improving liver function in rats with fatty liver after liver transplantation...

2022-10-26

【Animal modeling】-The lipid-lowering effect of citrus polymethoxyflavonoid biscuits on hyperlipidemia mice

This study was the first to evaluate the lipid-lowering effect of adding citrus polymethoxyflavone powder to biscuits in a hyperlipidemia mouse model through the measurement of lipid metabolism experimental indicators, aiming to provide a new functio...

2022-10-26

【Animal Modeling】-Study draws a map of human hematopoietic stem cells from hematopoietic endothelium to birth

Researchers such as Hanna K. A. Mikkola and Vincenzo Calvanese of the University of California, Los Angeles, collaborated to map human hematopoietic stem cells from the hematopoietic endothelium to birth...

2022-10-26

【Animal modeling】-Establishment and application of multiplex PCR method for four pathogens in experimental animals

To establish a multiplex PCR method for the rapid detection of four experimental animal pathogens, Pasteurella multocida, Bordetella bronchiscus, Mycoplasma and Klebsiella pneumoniae...

2022-10-26

【Animal modeling】-Protective effect of γ-secretase inhibitor on white matter damage in neonatal rats induced by hyperoxia exposure

To investigate the effect of γ-secretase inhibitor on white matter damage in neonatal mice induced by atmospheric pressure and high concentration oxygen exposure...

2022-10-26