【Animal modeling】-Effect of thalidomide on bisphosphonate-related osteonecrosis of the jaw

To study the effect of thalidomide on bisphosphonate-related osteonecrosis of the jaw...

2022-07-04

【Animal modeling】-Effect of repeated propofol anesthesia on spatial memory and long-term enhancement in young rats under hypoxia

Propofol is the most commonly used intravenous anesthesia for induction and maintenance anesthesia...

2022-07-04

【Animal Modeling】-Ultrasonic radiation force combined with targeted ultrasound microbubbles to evaluate renal ischemia-reperfusion injury in mice

To investigate the sensitivity and feasibility of ultrasonic radiation force to promote the adhesion of targeted microbubbles to improve the detection of renal ischemia-reperfusion (IR) injury...

2022-07-04

【Animal modeling】-Study on the protective effect of salvianolic acid A on the kidney of ZDF rats and the inhibition of lipoprotein-associated phospholipase A2

To observe the protective effect of salvianolic acid A on Zucker diabetic obese rats (nephropathy) and the effect on the expression of lipoprotein-related phospholipase A2...

2022-07-02

【Animal Modeling】-Comparison of the effect of gene therapy and traditional non-surgical therapy on postpartum stress urinary incontinence model rats

To study the effect of TGF-β1 gene therapy on rat model of postpartum stress urinary incontinence, and to explore the ideal new non-surgical treatment method for the disease...

2022-07-02

【Animal modeling】-M4 receptor blocker MT3 inhibits form deprivation myopia in guinea pigs

To investigate the inhibitory effect of the highly selective M4 receptor blocker MT3 on form deprivation myopia in guinea pigs and its potential mechanism...

2022-07-02

【Animal Modeling】-Intervention of Fufang Dihuang Granules on Microglia Activation and Neurobehavior in Parkinson

To investigate the intervention effect of Fufang Dihuang Granules on the activation of nigrostriatal microglia, the expression of inflammatory factors and neurobehavior in different rat models...

2022-07-01

【Animal modeling】-Effect of hypoxia on the expressions of drug transporters MDR1 and MRP2 in rats

To study the effect of simulated rapid altitude hypoxia on some physiological indexes and the expression of MDR1 and MRP2 efflux drug transporters in the small intestine, liver and kidney of rats, and to preliminarily explore the effect of high altit...

2022-07-01

【Animal Modeling】-Transcranial ultrasound perfusion imaging performance and safety evaluation in rats after skull thinning

To observe and quantitatively evaluate the performance of right brain transcranial ultrasound perfusion imaging by thinning the local skull of SD rats to improve the acoustic window, and to preliminarily evaluate the effect of bone grinding and trans...

2022-07-01

【Animal Modeling】-Effect of ubiquitin carboxyl-terminal hydrolase 1 gene deletion on the reproductive system development of female mice

To study the effect of ubiquitin carboxyl-terminal hydrolase L1 gene deletion on the reproductive system of female mice...

2022-07-01

【Animal modeling】-Protective effect of Paijiangcao on acetaminophen-induced drug-induced liver injury in rats

Paijiangcao is the whole rooted herb of the perennial herbs of the family Paiaceae, Huanghuabaijiang and Baihuabaijiang, with various pharmacological activities. The purpose of this study was to investigate the protective effect of Patrinia on acetam...

2022-07-01

【Animal Modeling】-The mechanism of mouse germ cell-specific transcription factor SOHLH1 regulating Sox30 gene expression

SOHLH1 and SOX30 are transcription factors related to spermatogenesis. Both Sohlh1 and Sox30 gene knockout male mice lose fertility...

2022-07-01

【Animal Modeling】-The neuroprotective effect of total flavonoids of Mongolian herb Xiangqinglan on Parkinson

To investigate the neuroprotective effect of the total flavonoids of Mongolian medicine Xiangqinglan on MPTP-induced Parkinson\\\\\\\'s model mice...

2022-07-01

【Animal Modeling】-Changes and significance of metallothionein expression in the development of hepatocellular carcinoma in C57BL/6J mice

To understand the dynamic changes and regularities of gene expression levels of metallothioneins (MTs) in the development of mouse hepatocellular carcinoma (HCC), and to explore the significance of MTs in the development of HCC...

2022-07-01

【Animal modeling】- Breeding and genotype identification of Bmal1 clock gene knockout mice

To breed and identify the genotype of Bmal1 knockout mice to provide an ideal animal model for biological rhythm research...

2022-07-01

【Animal Modeling】-The effect of increasing-dose benzalkonium chloride on rabbit anterior chamber

Corneal endothelium (CE) is a layer of cells on the inner surface of the cornea. Its main function is to control the hydration of the cornea, thereby maintaining its transparency...

2022-07-01