【Animal Modeling】-Regulatory effects of corstine on skin inflammation and autophagy in psoriasis mice by inhibiting C5a/C5aR1 pathway

To investigate the regulatory effect of Cosentyx on skin inflammation and autophagy in psoriatic mice through the C5a/C5aR1 pathway through the imiquimod (IMQ) mouse model of psoriasis...

2022-06-20

【Animal Modeling】-Effect of Qingre Runzao Oral Liquid on the upstream and downstream cytokines of ILC2s in asthmatic mice

To intervene ovalbumin (OVA)-sensitized asthmatic mice with Qingre Runzao Oral Liquid, and to observe its effect on the number of type II innate lymphocytes (ILC2s) and its upstream and downstream cytokines in asthmatic mice...

2022-06-20

【Animal Modeling】-Research on the analgesic effects of Lugai Qishan Fluoxane on labor and delivery based on MAPK signaling hypoxia

To investigate the effect of sevoflurane labor analgesia on hypoxia in neonatal rats based on the mitogen-activated protein kinase (MAPK) signaling pathway...

2022-06-20

【Animal Modeling】-Safflower Yellow Pigment Protects the Kidneys of Mice with Diabetic Nephropathy and Its Mechanism

To investigate the renal protective effect and mechanism of safflower yellow on streptozotocin-induced diabetic nephropathy in mice...

2022-06-20

【Animal Modeling】-Discuss the pharmacodynamic effect and preliminary mechanism of action of oxymatrine, the active ingredient in Sophora flavescens, in the treatment of atopic dermatitis mice

To observe the chronic toxicity of Deinococcus radiodurans R1 to SD rats...

2022-06-17

【Animal modeling】-Protective effect of oxymatrine on atopic dermatitis model mice

To investigate the efficacy and preliminary mechanism of oxymatrine, the active ingredient in Sophora flavescens, in the treatment of atopic dermatitis mice...

2022-06-17

【Animal modeling】-Relevant mechanism of hypertonic saline protecting blood-brain barrier and reducing cerebral edema in rats with cerebral hemorrhage

To investigate the related mechanism of hypertonic saline treatment in reducing cerebral edema in rats with cerebral hemorrhage...

2022-06-17

【Animal Modeling】-Effect of Yanlishuangkouhan Dropping Pills on immune cell subsets and NF-κB signaling pathway in rabbits with chronic pharyngitis

To explore the effect and mechanism of Yanlishuangkouhan dropping pills on chronic pharyngitis rabbit model...

2022-06-17

【Animal modeling】-Dynamic changes of tumor-infiltrating immune cells in MC38 colon cancer mice

To observe the dynamic changes of tumor-infiltrating immune cells during tumor development in tumor-bearing mice...

2022-06-17

【Animal modeling】-Intervention effect of chitosan on PM2.5-induced acute lung injury in mice

To investigate the intervention effect of chitosan on PM2.5-induced acute lung injury in mice...

2022-06-17

【Animal Modeling】-The brain protection effect and mechanism of regular aerobic exercise on cerebral ischemia rats

To study the protective mechanism of regular aerobic exercise on brain tissue in rats with cerebral ischemia...

2022-06-17

【Animal modeling】-Comparative study on steroid hormone synthesis ability of mice with drug-induced deficiency syndrome induced by cisplatin continuous and interval modeling

To study the effect of different dosage regimens of cisplatin on steroid hormone synthesis and reserve function in mice...

2022-06-17

【Animal Modeling】-miR-122 Expression Changes and Action Mechanisms in Kidney Tissues of Mice with Diabetic Nephropathy

To investigate the expression changes of miR-122 in the kidney tissue of diabetic nephropathy mice and the effect and possible mechanism of silencing miR-122 on the kidney tissue of DN mice...

2022-06-17

【Animal Modeling】-Effect of long-term high-protein diet on hepatic steatosis and fat accumulation in OVX mice

To investigate the effect of long-term high-protein diet on liver and adipose tissue in ovariectomized mice and the effect of glucagon-like peptide-1...

2022-06-17

【Animal Modeling】-Effect and mechanism of androgens on gastric mucosal mitochondrial function in aged rats

To investigate the effect and mechanism of androgens on gastric mucosal mitochondrial function in aged rats with orchiectomy (GDX)...

2022-06-17

【Animal Modeling】-Protective Mechanism of Bamboo Phytophthoracin A on Liver Ischemia-Reperfusion in Rats

To investigate the protective mechanism of phyllostachysin A on hepatic ischemia-reperfusion injury in rats...

2022-06-17