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To establish a method system for gene editing of the second exon of mouse MAD2L1 gene using CRISPR/Cas9 system, and to analyze the off-target effect of CRISPR/Cas9 on MAD2L1 gene editing...
2022-04-26To investigate the effect of recombinant human parathyroid hormone (rhPTH) on fracture healing in 2-month-old male rats using Micro-CT...
2022-04-26To study the distribution and expression of lysozyme 1 gene in hatched blastocysts and dormant embryos of mice before and after superovulation, and to explore the new regulatory mechanism of animal embryo implantation...
2022-04-26To analyze the role of Mgst1 gene in the programmed freezing of mouse embryos by comparing the relative expression of Mgst1 gene and the differential expression distribution of Mgst1 protein before and after programmed freezing and thawing of hatched...
2022-04-26To investigate the role and mechanism of endothelial nitric oxide synthase and nitric oxide in microvascular disease in mice with unilateral ureteral obstruction and renal interstitial fibrosis...
2022-04-26To further study the kidney-yang deficiency constitution of Lewis rats by observing the gene expression and ultrastructure related to kidney-yang deficiency in the hypothalamus of Lewis rats...
2022-04-26To observe the effect of Naoshuantong capsule on the expression of inflammatory related factors interleukin-1β, interleukin-6, tumor necrosis factor, intercellular adhesion molecule-1 and metalloproteinase-9 in ApoE-/- atherosclerosis mouse model. Th...
2022-04-26To explore the role of up-regulated expression of KA1 sub-receptors in the death of hippocampal neurons induced by endoplasmic reticulum stress...
2022-04-26Explore a new method of fast, convenient and efficient extraction of rat dorsal root ganglia (dorsal root ganglion, DRG)-exploring and extracting DRG against the direction of nerve walking...
2022-04-26To investigate the neurotoxicological effects of flame retardant TCPP exposure in mice and related mechanisms...
2022-04-26To explore the effect of fluoxetine on behavior and hippocampal neurogenesis in post-stroke depression model rats...
2022-04-26To observe the effect of angiotensin (1-7) [Ang (1-7)] on the expression of glial fibrillary acidic protein (GFAP), glial cell-derived neurotrophic factor (GDNF) and cognitive function in the hippocampus of diabetic rats. influence...
2022-04-26To observe the effect of Naoshuantong capsule on the expression of inflammatory related factors interleukin-1β, interleukin-6, tumor necrosis factor, intercellular adhesion molecule-1 and metalloproteinase-9 in ApoE-/- atherosclerosis mouse model...
2022-04-26To establish a rabbit model of steroid-induced necrosis of the femoral head, and to evaluate the repairing effect of Taohong Siwu Decoction (THSWD) on the microscopic bone structure damage of SIONFH combined with high-resolution MRI and micro-CT...
2022-04-26To compare the biological characteristics of the eyeballs of Zmu-1:DHP and DHP guinea pigs, and to preliminarily explore the retina-related mechanism of spontaneous myopia in Zmu-1:DHP guinea pigs...
2022-04-25Reproduction method For experimental mice weighing 25 to 30 g, first observe the experimental animals for 3 days, select healthy animals as models, and then pass the diphtheria toxin stock solution of 7.30 μg/g body weight through the tail of the mou...
2022-04-25