
A new study on mice shows that breastfeeding women who eat too much may increase their risk of obesity and puberty in the future, which can lead to diabetes and other infertility...
2022-02-04![[Animal Modeling] The effect of botulinum toxin type A heavy chain intervention on the expression of growth-related proteins after spinal cord injury in rats](/./uploads/images/default/default.png)
To investigate the effect of artificial recombinant botulinum toxin type A heavy chain (BoNT/A heavy chain) on the expression of local growth-related proteins in rat spinal cord injury and promote neurite regeneration. It provides evidence to clarify...
2022-02-04
Osteoarthritis (OA) is a common musculoskeletal disease characterized by damage to the joint structure, leading to symptoms such as joint stiffness and pain...
2022-02-04
How to study the protective effect of Panax Notoginseng Saponins (PNS) and its monomer Rg1? b1 affects the tight junction damage of vascular endothelium caused by oxygen glucose deprivation (OGD)...
2022-02-04
To explore the effect of high-fat diet feeding time on blood glucose, insulin resistance index (HOMA-IR) and urinary albumin excretion rate (UAER) in type 2 diabetic nephropathy (DN) rats...
2022-02-04
Bleomycin (bleomycin) is a polypeptide anti-tumor drug, and its mechanism of causing pulmonary interstitial fibrosis is mainly through the action of reactive oxygen species. In the early stage of lung injury caused by bleomycin, that is, the alveolit...
2022-02-04
Use transient receptor potential vanilloid type 4 (TRPV4) gene knockout (TRPV4-/-) mice to study the role of TRPV4 receptor in kidney damage caused by angiotensin II (angiotensin II, Ang II) effect...
2022-02-04
Congestion syndrome (blood loss syndrome) is caused by qi deficiency, qi stagnation, hot toxins, cold blood, etc., blocking blood flow and accumulating in the meridians or organs...
2022-02-04![[Animal Modeling] Japan has developed a new bioluminescence system that can observe brain activity in living animals](/./uploads/images/default/default.png)
Japan Institute of Physical Chemistry has developed a new type of bioluminescence system that can observe the brain activity of living animals...
2022-02-04
In the design of biomedical scientific research, the question of how to build animal models is usually considered, because there are currently no or should not be conducted on patients to clarify the mechanism and efficacy of many experiments. Will b...
2022-02-04![[Animal Modeling]-How to model acute renal failure?](/./uploads/images/default/default.png)
Acute renal failure model of dog renal artery contraction: Take a 10-20 kg male dog, anesthetize with pentobarbital sodium 30 mg/kg, and expose the left renal artery surgically. Clamp it for 1 hour, then relax, reperfuse, and collect urine from the u...
2022-02-04![[Animal Modeling]-Gender Wars in Genes Both male and female fruit flies need a certain gene, but they are used for different purposes-how can such genes evolve?](/./uploads/images/20200905/e4a4cc3dce563.png)
As we all know, when a species needs to change to adapt to its specific needs, evolution can be of great help...
2022-02-04
Researchers in the laboratory have discovered a new method of using the regeneration ability of stem cells in the laboratory to regenerate dog teeth in the open laboratory of \\\"Gene and Stem Cell Technology\\\" of Kazan Federal University...
2022-02-04![[Animal Modeling]-Periodontitis model formed by oral inoculation of bacteria](/./uploads/images/default/default.png)
Replication method Oral Porphyromonas gingivalis to periodontitis model animals. 4 days before the experiment, an adult rat weighing 250 g was injected intramuscularly with kanamycin or ampicillin at a dose of 20 mg per head...
2022-02-04
The exquisite Mongolian gerbils are raised in separate cages and can eat freely. In addition to general hygiene requirements, in order to avoid cramps, please keep the room quiet when feeding and do not make any noise or move the cage...
2022-02-04
Adenine produces 2,8-dihydroxyadenine through the action of xanthine oxidase deposited in the glomerulus and renal interstitium, forming foreign body granulomatous inflammation, and reacting to block the tubules of the renal tubules. Cystic expansion...
2022-02-04