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ApoE- can create ob/ob mice + MCD diet, db/db mice + MCD diet, Abcb11 mice + MCD diet and other animal models by combining genetic modification and nutritional factors according to the rules of human NAFLD. /-Mouse + HFD, PPARa-/-mouse + MCD diet, et...
2022-02-02Key gene mutations in fat metabolism in liver cells can cause abnormal fat metabolism and disrupt the balance of fat input/output in the liver...
2022-02-02Generally, methylnitrosonitroguanidine (N-methyl-N\\\'-nitrosonitroguanidine, MNNG) and methylcholestene (MC) are used. MNNG is a kind of polycyclic hydrocarbon, which has a strong carcinogenic effect and can cause the production of nitric oxide in t...
2022-02-02Cysteamine, also known as β-mercaptoethylamine, can specifically consume the body\\\'s somatostatin. It is also called a somatostatin depletion agent. D-cell damage to the duodenal mucosa may be one of the targets of the selective action of cysteamin...
2022-02-02Replication method Adult rats are injected intraperitoneally with 100 mg/kg body weight of thioacetamide (TAA), the initial dose is doubled, and then every other week for 13 weeks...
2022-02-02Every year, many Chinese patients suffer serious sequelae, such as paralysis caused by SCI. How to regenerate nerve cells and nerve fibers after spinal cord injury and how much function is restored are very important issues...
2022-02-02After human tumors are implanted subcutaneously, tumor cells are not easy to invade surrounding tissues, because envelopes are often formed around the graft, and the same tumor cells are not easy to penetrate into the abdominal cavity or other tissue...
2022-02-02Hepatitis E is mainly transmitted through the fecal-oral route (digestive tract), and other routes include blood transmission and vertical transmission. Taking advantage of the transmission characteristics of hepatitis E, the method of intravenously...
2022-02-02In order to reduce the occurrence of accidents, it is necessary to limit the number of people who can enter the laboratory at the same time...
2022-02-02Understand the basic principles and replication methods of the rat pulmonary edema model...
2022-02-02Most studies on how animals choose companions focus on the quality indicators of the evaluation, assuming that all individuals agree to find attractive companions, and hardly pay attention to the reasons why personal preferences will change...
2022-02-02
Gastroesophageal reflux refers to the reflux of gastric contents (such as bile salts and pancreatin) that flows from the duodenum into the stomach and enters the esophagus. It is divided into physiological reflux and pathological reflux...
2022-02-02Monocrotaline (MCT) is a plant extract of the genus Crotalaria. It is a double-layer pyrrolidine alkaloid that can carbonize the DNA of cancer cells and exert anti-cancer effects, mainly after injection in the body...
2022-02-02The method of ketamine (commonly known as K powder) is a non-competitive N-methyl-D-aspartate receptor antagonist and has an anesthetic effect. It is widely used in clinical medicine, especially in pediatric patients and the heart Among sick patients...
2022-02-02The proliferation, metastasis and recurrence of gastric cancer depend on angiogenic factors. There are many factors affecting the transplantation of human gastric cancer into nude mice, including human gastric cancer tissue and cells transplanted int...
2022-02-01To evaluate the safety of allergy to hydroxyethyl starch 40 sodium chloride injection...
2022-02-01