
Objective To study the effects of Oct4 and Cdx2 knockdown on the expression of genes related to the differentiation of bovine ICM and TE, and to explain the role of Oct4 and Cdx2 in the early development of bovine embryos...
2021-12-31
Objective To explore the effect of alprostadil (PGE1) on liver function in rats with fulminant hepatic failure (FHF), and to explore its effect on eukaryotic translation initiation factor 2α (eIF2α) / activating transcription factor 4 (ATF4) / C/ EB...
2021-12-31![[Animal Modeling]-Ke Shan Ting regulates skin inflammation and autophagy in mice with psoriasis by inhibiting C5a/C5aR1 pathway](/./uploads/images/default/default.png)
This study intends to use imiquimod (IMQ) mouse psoriasis model to explore the regulation effect of Cosentyx on skin inflammation and autophagy in psoriasis mice through the C5a / C5aR1 pathway...
2021-12-31
Objective To explore the effects of salidroside (Sal) on the nuclear transcription factor E2 related factor 2 / Kelch-like epichlorohydrin related protein 1 (Nrf2 / Keap1) signaling pathway and wound healing in rats with diabetic foot ulcer (DFU)...
2021-12-31
Establish an animal model of cynomolgus muscle atrophy, and use the method of restricting the movement of the lower limbs to establish a model evaluation method?...
2021-12-30![[Animal Modeling]-Chronic Renal Insufficiency Model](/./uploads/images/default/default.png)
Establish a C57BL/6 mouse model of chronic kidney disease, explore the changes in tubule damage indexes and interstitial fibrosis with the dose of cisplatin, and provide animal experimental evidence for the study of the progression from AKI to CKD...
2021-12-30
How to establish a BALB/c mouse total hysterectomy experimental animal model, and investigate and analyze the characteristics and formation mechanism of the model...
2021-12-30
Neurobiochemical function change model...
2021-12-30
Animal: SD rat, female, 2 to 3 months old, weighing 180 to 220 g; drug: 6-hydroxydopamine (6-OHDA), apomorphine, rabbit anti-tyrosine hydroxylase serum, parent Avidin-biotin-peroxidase complex (ABC) kit; equipment: rat brain stereotaxic instrument, 3...
2021-12-30
The pathological changes of atherosclerosis include lipid streaks, fibrous plaques, atherosclerotic plaques, compound lesions, etc., while foam cells are the early cytological features of As lesions...
2021-12-30
The replication method uses 6-8 weeks old KM mice, each mouse is inoculated with Vibrio vulnificus (VV) through different routes (intraperitoneal, intramuscular and subcutaneous injection) 0.2 ml (4.74 X 1000000)...
2021-12-30
Overview of the animal model of focal segmental glomerulosclerosis: FSGS causes asymptomatic proteinuria or nephrotic syndrome (NS) with or without renal insufficiency...
2021-12-30
Diabetic retinopathy occurs in approximately one-third of diabetic patients. This is the main cause of blindness among adults between the ages of 24 and 70...
2021-12-30
Discuss the differences between subcutaneous xenotransplantation of different parts of lung cancer and provide evidence for lung cancer researchers...
2021-12-30
Modeling material animal: Wistar rat, body weight (216±10) g; equipment: electroconvulsive instrument...
2021-12-30
Using gene knock-in CaV1.1-R528H mice to establish and evaluate hypokalemic periodic paralysis model...
2021-12-30