
To provide an animal model for follow-up research by constructing Fndc5 gene knockout mice...
2021-12-13
To detect and analyze the expression of HBV-related indicators in the urine of HBV transgenic mice, and to further understand the biological characteristics of the transgenic mice; and to determine the tissue source of HBV-related indicators in the u...
2021-12-13
Recently, researchers have reported the successful transplantation of retinal tissue derived from human embryonic stem cells in a primate model of retinitis pigmentosa. Retinitis pigmentosa is a hereditary eye disease with few treatment options....
2021-12-09
Two Mycobacterium tuberculosis cultures (BACTEC MGIT960 culture and Roche (L? Wenstein-Jensen, LJ) culture) were used to simultaneously verify the therapeutic effect of rifampicin (RIF) in a mouse model of tuberculosis infection...
2021-12-09
To observe the therapeutic effect of bakuchiol on ovariectomized male mice with osteoporosis...
2021-12-09![[Animal Modeling]-Model of liver fibrosis induced by common bile duct ligation](/./uploads/images/default/default.png)
Replication method Adult rat, open the abdominal cavity after anesthesia, find and release the common bile duct in the duodenal descending mesentery, pass two silk threads under it, and make a \\\"V\\\"-shaped incision to the liver...
2021-12-09
Establish a mouse model of diffuse infection of drug-resistant Candida albicans to screen new drugs...
2021-12-09![[Animal Modeling]-Spinal Cord Compression Injury Model](/./uploads/images/default/default.png)
Spinal cord compression is one of the important causes of spinal cord injury. The injury model mainly simulates spinal cord injury caused by spinal cord space-occupying lesions, which can be divided into acute compression injury and chronic compressi...
2021-12-09
Naphthalene can increase the reactive oxygen species in rabbit cells, increase the production of free radicals, increase peroxide damage, damage the lipids in the lens cell membrane, and cause experimental cataracts...
2021-12-09
Feeding method Adult rats fasted with water for 24 hours, anesthetized with ether, and fixed the animal\\\'s limbs and neck on the rat board....
2021-12-09
Using mechanical or chemical methods to directly damage the sinus node area, local myocardial ischemia and necrosis, agitation and conduction disorders, decreased heart rate, sinus block, sinus block or junctional stroke and slow syndrome, causing pr...
2021-12-09![[Animal Modeling]-Rat lumbar ventral nerve root traction model](/./uploads/images/default/default.png)
To study the etiology and drug development of amyotrophic lateral sclerosis, establish a rat model of fourth lumbar-abdominal root traction, and use brain-derived neurotrophic factor as a positive drug to verify the effectiveness of the model. Do you...
2021-12-09
Analyze the anti-tumor effect of microRNA-144 (miRNA-144) gene overexpression on liver cancer mice and its influence on the intestinal flora. How to establish ascites liver cancer transplanted into mice?...
2021-12-09
To study the therapeutic effect and action path of eucommia extract on mice with mastitis...
2021-12-09![[Animal modeling]-RNA interference specifically blocks the effect of local angiotensin Ⅱ type 1 receptors on the first-phase insulin secretion in pancreatic islets](/./uploads/images/default/default.png)
Observe the changes of insulin secretion in db/db mouse pancreatic islets after blocking the expression of local angiotensin II type 1 receptor (AT1R) by RNA interference technology, and explore its underlying mechanism...
2021-12-07
Study the advantages and disadvantages of various modeling techniques, and choose the most suitable animal model method to infect Ureaplasma...
2021-12-07