[Animal modeling] - Yulangsan chalcone inhibits NF in rats with myocardial ischemia-reperfusion injury- κ Impact of B signal path

To investigate the effect of Yulangsan chalcone on nuclear factor in myocardial ischemia-reperfusion injury rats κ B Effect of signal path...

2022-12-19

[Animal modeling] - Effects of skeletal muscle specific Chrono overexpression on exercise ability and glucose tolerance in mice

The level of skeletal muscle glucose metabolism is an important factor affecting aerobic exercise ability, and the level of skeletal muscle glucose metabolism is regulated by the biological clock...

2022-12-19

[Animal modeling] - Study on the mechanism of detoxification and protection of grub peptide extract on lead induced nephrotoxicity in mice

To study the mechanism of detoxification and protection of grub peptide extract in mice by establishing a lead acetate induced nephrotoxicity model, and to provide experimental basis for the prevention and treatment of lead induced nephropathy...

2022-12-19

[Animal modeling] - To explore the effect of different concentrations of Matrix on heterotopic subcutaneous transplantation of Lewis lung cancer in mice

To investigate the effects of different concentrations of Matrigel on heterotopic subcutaneous transplantation of Lewis lung cancer in mice...

2022-12-19

【Animal modeling】-Protective effect of amygdalin on necrotizing enterocolitis in neonatal rats

To analyze the protective effect of amygdalin on necrotizing enterocolitis (NEC) in neonatal rats...

2022-12-17

【Animal modeling】-Expression and purification of Asprosin and its effect on mouse cardiac function in vivo

To express and purify asprosin protein in prokaryotic cells of Escherichia coli, and to study its effect on the improvement of cardiac function...

2022-12-17

[Animal Modeling]-Histomorphology and pathological evaluation in miniature pig coronary artery model

The procedure for preparing blood vessel samples of stent segments is as follows. Stent segment blood vessel hard tissue sectioning and staining device: timing constant temperature electromagnetic stirrer, digital display electric heating constant te...

2022-12-17

【Animal Modeling】-Screening and application of single nucleotide polymorphism markers for identification of four commonly used strains of rats

To screen out the single nucleosides that can rapidly identify four commonly used rat strains [Wistar rat, Goto-Kakizaki (GK) rat, Brown-Norway (BN) rat, Sprague-Dawley (SD) rat] acid polymorphism sites and verify their reliability...

2022-12-17

【Animal modeling】-Changes and significance of monocarboxylate transporter expression in rat cerebral cortex under exercise fatigue

To explore the relationship between the body\\\'s adaptability to exercise fatigue and the expression of monocarboxylate transporter in cerebral cortex...

2022-12-15

【Animal modeling】-Preparation and identification of liver-specific LCMT1 knockout mouse model

To establish a liver-specific LCMT1 knockout mouse model...

2022-12-15

【Animal Modeling】-Preliminary study of knocking out MATP gene in mouse melanoma cell line using CRISPR-Cas9 system

Use the CRISPR/Cas9 system to knock out the MATP gene in mouse melanoma cell lines, and lay the foundation for the functional study of the MATP gene...

2022-12-15

[Animal modeling] - Construction and identification of a humanized mouse model immunized with prostate cancer

To construct a humanized mouse model of immune system and transplant it into a human prostate cancer cell line for the study of immunotherapeutic drugs for prostate cancer...

2022-12-15

[Animal modeling] - Effect and mechanism of Shenqu Xiaoshi oral liquid on gastrointestinal motility in mice with functional dyspepsia

To explore the effect and mechanism of Shenqu Xiaoshi oral liquid on gastrointestinal motility in mice with functional dyspepsia (FD)...

2022-12-14

[Animal modeling] - Study on the improvement effect and mechanism of paeoniflorin on Bayk8644 induced depression and anxiety like behavior in rats

To explore the pharmacological mechanism of paeoniflorin in improving depression and anxiety like behavior in rats based on L-type voltage dependent calcium channel...

2022-12-14

[Animal modeling] - Leptin receptor knockout causes microglia activation in rat brain tissue

To study the morphological and functional changes of microglia in rat brain after leptin receptor (LEPR) gene knockout, and explore the function of leptin receptor in microglia...

2022-12-14

[Animal modeling] - Changes of C-reactive protein and inflammatory factors in the high altitude multiple organ dysfunction syndrome model of the Fenma pig

To study the tumor necrosis factor (TNF) in the high altitude multi organ dysfunction syndrome (MODS) model of pteridophyte pigs- α Interleukin-1 β And the change characteristics of C-reactive protein in the process of inflammatory reaction...

2022-12-14