[Animal modeling] - Establishment of a mouse model of adverse skin reactions induced by erlotinib

Elotinib is a new targeted drug for the treatment of non-small cell lung cancer. In recent years, it has been widely used in clinical practice, but there are many side effects, among which rash is the most common, and it is most difficult for patient...

2022-11-22

[Animal modeling] - different concentrations A β Differences in learning and memory of 25-35 protein mimicking Alzheimer's disease model

Different concentrations of amyloid A β After injection of 25-35 lateral ventricles, observe the changes of learning and memory ability of Morris water maze in rats, and explore the A β 25-35 is the best concentration for injection...

2022-11-21

[Animal modeling] - Application evaluation of continuous glucose monitoring system in rabbit hypoglycemia model

To establish a rabbit hypoglycemia model and evaluate the accuracy and timeliness of subcutaneous continuous glucose monitoring system (CGMS) in hypoglycemia monitoring...

2022-11-21

[Animal modeling] Establishment of primary renal epithelial cell infection model of tree shrew by EV71 virus

To establish the infection model of EV71 on primary renal cells of tree shrews...

2022-11-21

[Animal modeling] - Establishment and analysis of 3D CT visualization model of adult tree shrew skeletal system

To establish a three-dimensional visualization model of tree shrew skeletal system, and provide basis for the diagnosis of tree shrew skeletal system diseases...

2022-11-21

[Animal modeling] - Establishment of acute liver failure model after 85% hepatectomy in Bama miniature pigs

To explore the effect of different proportions of hepatectomy volume on acute liver failure in Bama miniature pigs, and to provide a suitable method for establishing an appropriate model of acute liver failure after major hepatectomy in miniature pig...

2022-11-21

[Animal modeling] - Difference of expression of short wave optoprotein in guinea pig models of flash induced myopia and form deprivation myopia

To observe the difference of short wave optoprotein (S-opsin) expression between stroboscopic induced myopia and form deprivation myopia in guinea pigs, and to explore the causes...

2022-11-21

[Animal modeling] - Immunomodulatory effect of psoralen on rheumatoid arthritis in mice

To investigate the effect of psoralen on type II collagen induced rheumatoid arthritis in mice and its molecular mechanism...

2022-11-21

[Animal modeling] - Establishment of glioma orthotopic transplantation model with double fluorescence labeling

To establish a stable and real-time nude mouse model of glioma orthotopic transplantation...

2022-11-21

[Animal modeling] Preventive and therapeutic effects of diaminazine in rats with pulmonary hypertension

To investigate the preventive and therapeutic effects of diaminazine (DIZE) on pulmonary hypertension in rats...

2022-11-21

【Animal Modeling】-Comparative analysis of genetic monitoring results of two closed populations of NIH mouse populations

To monitor and analyze the genetic quality of two NIH closed group mouse populations in Beijing in the past 3 years...

2022-11-21

【Animal Modeling】-Research on the standard of abnormal toxicity of Asarum injection preparations detected by mice

To determine the LD50 value of mice intravenously administered with Asarum injection preparation, and to draft the abnormal toxicity inspection standard of this product...

2022-11-21

【Animal modeling】-Determination and analysis of physiological constants and blood biochemical indexes in male and female SJ5-SPF chickens of different ages

To investigate the effects of age and gender on the physiological and biochemical parameters of SJ5-SPF chickens...

2022-11-21

【Animal Modeling】-Effect of Atractylodes Rhizoma Extract on gastric mucosa and gastrointestinal immune function in rats with spleen deficiency syndrome

To investigate the protective effect of Atractylodes Rhizoma extract on gastric mucosa and its effect on gastrointestinal immune function in spleen deficiency model rats, and to clarify the mechanism of ERA\\\'s intervention in spleen deficiency synd...

2022-11-21

【Animal modeling】-Protective effect of Nrf2 antioxidant pathway in CCl4-induced acute liver injury in rats

To study the protective effect of Nrf2 oxidative damage pathway in CCl4-induced acute liver injury in rats...

2022-11-19

【Animal modeling】-Stable expression of human coagulation factor IX gene in mouse adipose stem cells

To transfect C57BL/6 mouse adipose-derived mesenchymal stem cells with recombinant adenovirus carrying human coagulation factor IX (hFIX) gene (F9). Vector cells for hemophilia gene therapy...

2022-11-19