[Animal modeling] - Changes of monoamine neurotransmitter content and neurofactor expression in brain region of rats with anxiety and depression

To study the changes of monoamine neurotransmitters in hippocampus, amygdala and prefrontal cortex and the expression trend of neurotrophic factors in brain of anxiety depression model rats, and to explore its possible pathogenesis...

2022-11-11

【Animal Modeling】- Mouse spleen mesenchymal stem cells regulate the proliferation and activation of T lymphocytes

To study the regulatory effect of mouse spleen mesenchymal stem cells (Sp-MSCs) on the proliferation and activation of T lymphocytes...

2022-11-10

【Animal Modeling】-Buulfan on the Injury of Hematopoietic Stem Cell Function in Mice

To examine the effects of different administration methods on the function of hematopoietic stem cells in mice...

2022-11-10

【Animal Modeling】-Study on Intestinal Morphology and Energy Demand of Long-clawed Gerbils

To analyze the relationship between species differences and intestinal morphology and energy metabolism, and to clarify the energy requirements of gerbils...

2022-11-10

[Animal modeling] - Comparison of subcutaneous transplanted tumor models in different parts of Lewis lung cancer in mice

To explore the differences of subcutaneous transplantation of lung cancer in different parts of the body, and to provide a basis for lung cancer researchers...

2022-11-10

[Animal modeling] - Establishment of tree shrew model of Fusarium solani keratitis

To establish a tree shrew model of Fusarium solanacearum keratitis by infecting the cornea of tree shrews with clinically isolated Fusarium solanacearum...

2022-11-10

【Animal Modeling】-The role of cAMP/CREB/BDNF signaling pathway in vortioxetine against depression-like behavior in mice

To study the effect of vortioxetine, a novel antidepressant, on cyclic adenosine monophosphate/cyclic adenosine monophosphate response element binding protein/brain-derived neurotrophic factor (cAMP/CREB/BDNF) signal transduction pathway...

2022-11-10

[Animal modeling] - Plasma metabonomics study on the model of type 2 diabetes rats with abnormal black gallbladder syndrome

To establish and analyze the characteristics of plasma metabonomics in type 2 diabetes (T2DM) rats with Uygur medicine abnormal black gallbladder syndrome...

2022-11-10

[Animal modeling] - Establishment and evaluation of rheumatoid arthritis combined with hypertension disease model

To establish a rat model of rheumatoid arthritis combined with hypertension, and to evaluate the characteristics of this model...

2022-11-10

[Animal modeling] - Establishment of animal model of dysuricemia type hyperuricemia

To explore a reliable method to establish a rat model of dysuricemia, and lay a foundation for the study of the pathogenesis of dysuricemia and the optimization of the treatment plan...

2022-11-10

[Animal modeling] - Construction and preliminary application of xenotransplantation model of human liver cancer

To establish a xenotransplantation model of human hepatocellular carcinoma (HCC) and explore its role in precision medical treatment of HCC...

2022-11-10

[Animal modeling] Establishment and identification of collagen induced arthritis model in DBA/1J mice

To establish a collagen induced arthritis model in DBA/1J mice and identify the model from morphology, pathology and immunology...

2022-11-10

[Animal modeling] - Preparation of highly dynamic septic shock dog model by intravenous injection of Escherichia coli

To establish a canine model of hyperkinetic septic shock by intravenous injection of Escherichia coli...

2022-11-10

[Animal modeling] - Construction of different degree shivering models in rats with hyperthermia

To explore the body temperature threshold of shivering in hyperthermic rats during cooling treatment, and to establish a rat model of different degrees of shivering...

2022-11-10

[Animal modeling] Reproduction and identification of sick sinus syndrome disease model constructed by miR-5572 transgenic mice

To investigate the feasibility of constructing sick sinus syndrome disease model in miR-5572 transgenic mice...

2022-11-10

[Animal modeling] - Establishment and evaluation of an animal model of skin pruritus in guinea pigs

To optimize the dose of histamine and 4-aminopyridine (4-AP) by central composite design response plane method, in order to establish a new model of pruritus in guinea pigs...

2022-11-10