【Animal Experiment】-miRNA-144 gene overexpression has anti-tumor effect on liver cancer mice and its influence on intestinal flora

Analyze the anti-tumor effect of microRNA-144 (miRNA-144) gene overexpression on liver cancer mice and its influence on the intestinal flora...

2020-10-12

【Animal Experiment】-The effect of western diet on apolipoprotein E knockout mice

To study the influence of western diet and standard diet on hematology and pathology of ApoE protein E knockout mice (ApoE-/-)...

2020-10-12

[Animal experiment]-Study on the effect of vilpromide combined with fluoxetine hydrochloride on depression in mice

To study the effect of Veromet capsule combined with fluoxetine hydrochloride capsule on depression in mice...

2020-10-12

[Animal experiment]-Study on the developmental toxicity of intravenous cyclophosphamide to New Zealand rabbit embryos and fetuses

Inject cyclophosphamide intravenously into pregnant rabbits, observe its toxic effect and performance on pregnant rabbit embryos and fetuses, and provide reference for selecting cyclophosphamide as a positive control...

2020-10-12

[Animal Experiment]-Scientists found that oral administration of small doses of metabolic compounds can restore fertility in mice

In a recent study published in Celleports, researchers used a small amount of metabolic compounds that reverse the aging process of eggs and successfully improved the fertility of older female mice...

2020-10-12

【Animal Experiment】-Preliminary study on the toxicity of different extracts of Psoralen to rats

To study the toxicity of oral administration of different extracts of Psoralen to rats and provide a safety basis for its clinical application...

2020-10-12

[Animal Experiment]-Oxygen therapy damages the lung microbiome of mice

One of the symptoms of severe COVID-19 is shortness of breath, which can greatly reduce blood oxygen levels. This is called hypoxemia. After admission, provide oxygen therapy to these patients to restore their levels to normal...

2020-10-12

【Animal Experiments】-Analysis of the influence of flora sensing AHLs molecules on the diversity of mouse intestinal flora

To investigate the effect of plant sensitive signal molecule N-acyl homoserine lactone (AHL) on the composition of the intestinal flora of mice, and to provide a theoretical basis for disturbing the intestinal flora under infection...

2020-10-12

[Animal experiment]-Qingfei Touxie Decoction mediates NLRP3 inflammasome to inhibit NF-κB signaling pathway and improves inflammatory response in mice with Mycoplasma pneumoniae

To explore the therapeutic effect and mechanism of Qingfei Touxie Decoction on mycoplasma pneumonia (MPP) mice...

2020-10-12

[Animal Experiment]-The impact of unexpected stress on the immunity and microbial flora of the rat digestive tract

By observing the rats after 9 days of stress intervention, analyze the impact of unpredictable stress stimulation on the immune system of the gastrointestinal tract and microbial populations, and provide reference for the study of chronic stress on g...

2020-10-12

【Animal Experiment】-Comparison study of small animal micro-CT, ultrasound and aortic catheterization in evaluating left ventricular function

To study the consistency and correlation of microCT, aortic catheterization and echocardiography in measuring left ventricular function parameters, and to evaluate the value of microCT in evaluating left ventricular function...

2020-10-12

[Animal experiment]-Stem cells can repair the damaged circuit of Parkinson's disease in mouse brain

Mature brains in Madison, Wisconsin are difficult to repair themselves after trauma, stroke or degenerative diseases such as Parkinson’s disease. The unlimited adaptability of stem cells provides hope for better nerve repair...

2020-10-12

[Animal Experiment]-Correlation between the expression of BDNF and VEGF in hippocampus and forebrain cortex and depression induced by chronic stress in mice

To explore the correlation between the expression of brain-derived neurotrophic factor (BDNF) and vascular endothelial growth factor (VEGF) in the hippocampus and anterior cortex of depression caused by chronic stress in mice...

2020-10-12

[Animal experiment]-Serum metabonomics study of isoproterenol-induced cardiac hypertrophy in rats

Search for important biomarkers through serum metabolites to study the cause of cardiac hypertrophy in rats...

2020-10-12

[Animal experiment]-Intervention of electroacupuncture on activation of dorsal root ganglion satellite glial cells and P2X7 receptor expression in rats with inflammatory pain

To observe the effects of electroacupuncture on chronic inflammatory pain, plantar retraction threshold (PWT) of dorsal root ganglion rats and activation of satellite glial cells and their P2X7 receptors...

2020-10-12

【Animal Experiment】-The effect of long-term administration of Fumikang vagina suppository on blood physiological and biochemical indexes of rabbits

Observe the effects of long-term use of Fumikang vaginal suppositories on rabbit blood physiology and biochemistry, and provide scientific basis for clinical safe medication...

2020-10-12