[Animal Modeling] - Effects of long-term external or systemic application of glucocorticoids on metabolic levels and organs in mice

To observe the effects of long-term external or systemic administration of glucocorticoid (GC) on metabolism and organs in normal mice...

2023-03-21

[Animal modeling] - Interventional effect and possible mechanism of resveratrol on premature ovarian failure in mice

To observe the intervention effect of resveratrol on premature ovarian failure in mice and elucidate its possible mechanism...

2023-03-21

[Animal modeling] - protective effect of miR-214 on postoperative neuronal damage in propofol anesthetized rats

To explore the effects of different exercise modes on skeletal muscle growth factors MSTN and IGF1 in rats, and to provide theoretical basis for selecting appropriate exercise modes to improve skeletal muscle function...

2023-03-21

[Animal modeling] - Effect of arginine vasopressin 1b receptor knockout on anxiety and social behavior in female rats

To investigate the effects of arginine vasopressin 1b receptor gene knockout on plasma corticosterone content, anxiety, and social behavior in female rats...

2023-03-21

【Animal modeling】-Inhibitory effect of ethyl acetate extract of Radix Radix officinalis on mouse hepatocellular carcinoma cells and orthotopic transplanted tumors

To investigate the inhibitory effect of ethyl acetate extract of Saxifrage Radix on mouse hepatocellular carcinoma cells and orthotopic transplanted tumors...

2023-03-20

【Animal modeling】-Promoting effect and mechanism of umbilical cord blood mononuclear cells on angiogenesis in rats with acute myocardial infarction

To investigate the effect and mechanism of umbilical cord blood mononuclear cells (HCMNCs) on angiogenesis in rats with acute myocardial infarction (AMI)...

2023-03-20

【Animal modeling】-Comparing the similarities and differences of oral flora between humans and commonly used experimental animals by 16S rRNA high-throughput sequencing

To use 16S rRNA high-throughput sequencing method to determine the oral flora of several commonly used experimental animals (Tibetan miniature pigs, beagle dogs, macaques, New Zealand rabbits, Wistar rats), and to compare and analyze the oral flora o...

2023-03-20

[Animal Modeling] - Study on the Mechanism of Intermittent Fasting in Improving Metabolic Disorders Induced by Olanzapine in Mice

To investigate the protective effect and mechanism of intermittent fasting on metabolic disorders induced by olanzapine in mice...

2023-03-20

[Animal modeling] - Inhibition of miR-146b-5p expression in situ improves renal fibrosis in UUO mice

To investigate the expression of miR-146b-5p in a mouse model of renal fibrosis, and to investigate the effect of knocking down miR-146b-5p in vivo on renal injury and fibrosis in mice...

2023-03-20

[Animal Modeling] Experimental Study on the Effect of MTS1/2 Inhibitor on the Repair of Spinal Cord Injury in Rats

To investigate the effects of MST1/2 inhibitors on the expression of Yes related protein YAP, nerve growth related protein 43, glial fibrillary protein GFAP, apoptosis factor Caspase 3, and motor function recovery after spinal cord injury in rats...

2023-03-20

[Animal Modeling] - Lingzhu Tusi Pill Inhibits IKK β/ NF- κ B/MCP-1 pathway reduces adriamycin induced renal proteinuria in rats

To investigate the effect and mechanism of Lingzhu Tusi Pill on adriamycin induced nephrotic proteinuria...

2023-03-20

【Animal Modeling】-A weekly subcutaneous injection of rhPTH(1-34) promotes fracture healing in rats

To observe the effect of weekly subcutaneous injection of parathyroid hormone rhPTH (1-34) on fracture healing in rats...

2023-03-17

【Animal Modeling】-Analysis of Main Nutrient Components and Amino Acid Composition of SPF Golden Hamster Milk

To understand the composition of SPF golden hamster milk, and to compare it with other rodent (mouse, rat, guinea pig) milk, rabbit milk, cow milk and infant formula...

2023-03-17

【Animal Modeling】-Establishment of a mouse model of chronic thrombus induced by carrageenan

To screen the conditions of chronic thrombosis mouse model by treating mice with different concentrations of carrageenan solution by continuous intraperitoneal injection...

2023-03-16

【Animal Model】-Effect of β-arrestin2 gene knockout on the function of mouse peritoneal macrophages

To investigate the effect of β-arrestin2 gene knockout on the function of mouse peritoneal macrophages...

2023-03-16

【Animal modeling】-Protective effect and mechanism of pine bark extract on cerebral ischemia-reperfusion injury in mice

To investigate the neurotherapeutic effect and mechanism of IL-6/STAT3/miR-21 in pine bark extract on cerebral ischemia-reperfusion injury in mice...

2023-03-16