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【Animal Modeling】-Characteristics of the pathological process of cardiac structure and function in a pressure-overloaded heart failure mouse model

【Animal Modeling】-Characteristics of the pathological process of cardiac structure and function in a pressure-overloaded heart failure mouse model

Establish a mouse model of heart failure, and use ultrasound images and pathological techniques to comprehensively evaluate the characteristic changes in cardiac function and structure during the onset of disease...

2021-07-27
【Animal Modeling】-Research Progress of Laminopathy Mouse Model

【Animal Modeling】-Research Progress of Laminopathy Mouse Model

The LMNA gene encodes type A lamin (lamin), and its mutation leads to a series of complex and diverse genetic diseases...

2021-07-27
[Animal modeling]-Carbon tetrachloride induces inbred strain C57BL/6 mice to establish liver fibrosis model

[Animal modeling]-Carbon tetrachloride induces inbred strain C57BL/6 mice to establish liver fibrosis model

Compare the inducing effect of different doses of carbon tetrachloride on the self-bred C57BL/6 mouse liver cirrhosis model, and establish a stable liver cirrhosis model...

2021-07-27
【Animal Modeling】-Establishment and Evaluation of Rabbit Knee Osteoarthritis Model

【Animal Modeling】-Establishment and Evaluation of Rabbit Knee Osteoarthritis Model

To establish a rabbit knee osteoarthritis model and evaluate it through rabbit cartilage defects...

2021-07-27
【Animal Modeling】-Establishment of psychiatric dependence drug addiction model and expression of Bax gene in cerebellum

【Animal Modeling】-Establishment of psychiatric dependence drug addiction model and expression of Bax gene in cerebellum

To study the effect of psychotropic drugs (heroin) on Bax gene expression in the cerebellum of poisoned rats, and establish it with a continuous dose increase method....

2021-07-27
【Animal Modeling】-Improvement and evaluation of the establishment method of neonatal rat necrotizing enterocolitis model

【Animal Modeling】-Improvement and evaluation of the establishment method of neonatal rat necrotizing enterocolitis model

Improve and compare the methods of establishing necrotizing enterocolitis animal models commonly used at home and abroad, and clarify simple and effective NEC modeling methods...

2021-07-26
【Animal Modeling】-Analysis of the preparation and comparison of animal models of facial paralysis

【Animal Modeling】-Analysis of the preparation and comparison of animal models of facial paralysis

Search the related literature of different models of facial paralysis animals, analyze the advantages and disadvantages of various model preparation methods, and explore the preparation methods suitable for different research types, so as to provide ...

2021-07-26
【Animal Modeling】-Preparation method of long-term stable SD rat type 2 diabetes model

【Animal Modeling】-Preparation method of long-term stable SD rat type 2 diabetes model

Explore how to prepare a rat model of diabetes induced by high-fat diet combined with streptozotocin (STZ) to provide a stable animal model of diabetes for clinical research...

2021-07-26
【Animal Modeling】-Establishment of long-term depression mouse model and observation of behavioral and neuropathological characteristics

【Animal Modeling】-Establishment of long-term depression mouse model and observation of behavioral and neuropathological characteristics

Establish a new type of long-term depression model mouse, and compare the advantages and disadvantages of this mouse with the general depression mouse model...

2021-07-26
【Animal Modeling】-Comparative study on establishing mouse models of allergic conjunctivitis under different conditions

【Animal Modeling】-Comparative study on establishing mouse models of allergic conjunctivitis under different conditions

Establish mouse models of allergic conjunctivitis under different antigens, different excitatory pathways, and different ages, compare immune response status, feel the best mouse models of allergic conjunctivitis, and screen crop conditions...

2021-07-26
The establishment of a new type of hyperlipidemia susceptible (WSHc) rat model of non-alcoholic fatty liver disease and the study of its pathological characteristics

The establishment of a new type of hyperlipidemia susceptible (WSHc) rat model of non-alcoholic fatty liver disease and the study of its pathological characteristics

Use new hyperlipidemia sensitive rats to establish a non-alcoholic fatty liver disease model, observe changes in blood biochemical indicators and pathological properties, explore its application and scientific research value, and provide new options ...

2021-07-26
【Animal Modeling】-Nude mouse model construction of clear cell renal carcinoma and research on the sensitivity of targeted drugs

【Animal Modeling】-Nude mouse model construction of clear cell renal carcinoma and research on the sensitivity of targeted drugs

Use patient-derived clear cell renal cell carcinoma (ccRCC) cells (patient-derived cells, PDC) to detect the sensitivity of ccRCCPDC to molecular targeted drugs for clinical diagnosis and treatment and experimental evidence...

2021-07-26
【Animal Modeling】-Research Progress on Animal Models of Parkinson\'s Disease

【Animal Modeling】-Research Progress on Animal Models of Parkinson's Disease

Parkinson\'s disease (PD) is a neurodegenerative disease that seriously endangers human health...

2021-07-26
【Animal Modeling】-Research Progress of Miniature Pig Atherosclerosis Model

【Animal Modeling】-Research Progress of Miniature Pig Atherosclerosis Model

Miniature pigs are very similar to humans in terms of arterial anatomy and physiology, and are currently the most ideal model for studying atherosclerosis (AS) related diseases...

2021-07-26
【Animal Modeling】-Research progress in the construction of hemophilia arthropathy model

【Animal Modeling】-Research progress in the construction of hemophilia arthropathy model

Hemophilic arthropathy is a debilitating disease caused by spontaneous intra-articular hemorrhage and recurrent intra-articular hematoma. The main clinical manifestations are chronic pain, joint damage and poor quality of life....

2021-07-26
【Animal Modeling】-The effect of high-fat feed feeding time on type 2 diabetic nephropathy rat model

【Animal Modeling】-The effect of high-fat feed feeding time on type 2 diabetic nephropathy rat model

How to study the effect of different high-fat diet feeding time on blood glucose, insulin resistance index (HOMA-IR) and urinary albumin excretion rate (UAER) in type 2 diabetic nephropathy (DN) rat models?...

2021-07-22