【Animal Modeling】-Experimental Study on the Differentiation of Bone Marrow Mesenchymal Stem Cells into Cardiomyocyte-like Cells Induced by Jiawei Danshen Decoction in Vitro

To explore the effect of Jiawei Danshen Decoction on the differentiation of bone Messechymal stem cells (BMSC) into cardiomyocyte-like cells in vitro...

2021-07-16

[Animal Modeling]-To study the synergistic analgesic effect and mechanism of choline and parecoxib sodium through mouse experiments

To investigate the interaction between choline and parecoxib sodium in analgesia and to preliminarily explore its mechanism of action...

2021-07-16

【Animal Modeling】-CaN-NFATc3 Pathway in the Restenosis after Balloon Dilation of the Abdominal Aorta in Rats

To study the role of calcineurin (CaN) and its downstream activated T cell nuclear factor (NFATc3) in restenosis after balloon dilation, and provide a new theoretical basis for the prevention and treatment of vascular restenosis...

2021-07-16

To explore the protective effect and mechanism of miRNA-29c on cerebral ischemia-reperfusion nerve injury in rats

To study the effect of Huang injection (AI) on the apoptosis of hippocampal neurons in rats with hypoxia/hypoglycemia/levoxyglucose (H/R) under the action of Bcl-2 inhibitor (TW-37)...

2021-07-16

【Animal Modeling】-The protective effect and mechanism of miRNA-29c on cerebral ischemia-reperfusion nerve injury in rats

To investigate the protective effect and mechanism of miRNA-29c on cerebral ischemia-reperfusion nerve injury in rats...

2021-07-16

[Animal modeling]-Changes of IL-6, SOD and MDA in lung tissues of rats with acute pulmonary edema

To investigate the changes of malondialdehyde (MDA), superoxide dismutase (SOD) and interleukin 6 (IL-6) in the lung tissue of acute pulmonary edema induced by acute hypoxia in rats...

2021-07-16

[Animal modeling]-Proliferation and differentiation of neural stem cells in the subventricular zone of rats after traumatic brain injury

To investigate the time course of neural stem cell proliferation and differentiation in the subventricular zone after brain injury...

2021-07-15

【Animal Modeling】-The effect of Trichinella spiralis and its worm-derived protein on sepsis induced by cecal ligation and perforation in mice

To observe the effect of caecal worm and its worm-derived protein on sepsis caused by cecal ligation and perforation (CLP) in mice...

2021-07-15

[Animal Modeling]-The SOD activity of diabetic rats and the effect of antioxidant treatment on the body's antioxidant status

To study the changes in SOD activity and protein expression levels in the main organs of diabetic rats, and observe the effect of the antioxidant N-acetylcysteine (NAC) on the body\'s antioxidant status after short-term treatment (4 weeks)...

2021-07-15

【Animal Modeling】-Comparison of the effects of gene therapy and traditional non-surgical treatment on postpartum stress urinary incontinence model rats

To study the effect of TGF-β1 gene therapy on the rat model of postpartum stress urinary incontinence, and to explore an ideal new non-surgical treatment method...

2021-07-15

The role of phosphokinase Czeta in the anterior cingulate cortex in the emotional response of rats with inflammatory pain induced by Freund’s safe adjuvant

Observe the emotional response of CFA-induced inflammatory pain model rats, and explore the relationship between the anterior cingulate cortex (ACC) phosphokinase zeta (PKCzeta) and the emotional response of inflammatory pain rats...

2021-07-15

【Animal Modeling】-M4 receptor blocker MT3 inhibits form deprivation myopia in guinea pigs

To explore the inhibitory effect of highly selective M4 receptor blocker MT3 on guinea pig morphological deprivation myopia and its underlying mechanism...

2021-07-15

[Animal Modeling] The effect of 6-week free-wheeling exercise on sex hormones and hypothalamic-pituitary-testicular axis in high-fat-fed male rats

To observe the effects of high-fat diet on the hypothalamus, pituitary, testicular structure and sex hormone levels in adolescent male rats, and to explore the effects of 6-week free-spirited exercise...

2021-07-15

Animal experiments found that anesthetics may cause long-term memory loss

Pre-clinical data published in the Journal of Clinical Research and The Globe and Mail indicate that pre-clinical data can lead to long-term cognitive dysfunction, even after the use of anesthesia, or even after the drug is no longer effective...

2021-07-15

【Animal Modeling】-Development of an experimental fixture for observing the hind toes of mice

Mice are commonly used experimental animals in medical research, and they are also commonly used in experiments in medical physiology, pathology, pathophysiology and other disciplines....

2021-07-15

【Animal Modeling】-bcl-2 gene modified neural stem cell transplantation to repair rat spinal cord injury

To investigate the effect of bcl-2 gene-modified neural stem cell transplantation on the recovery of nerve function in rats with spinal cord injury...

2021-07-15