【Animal Modeling】-Effect of icariin on androgen receptor signaling pathway in orthotopic prostate cancer xenografts in SCID mice

To observe the effect of icariin on androgen receptor signaling pathway in orthotopic xenografts of prostate cancer in SCID mice...

2022-09-30

【Animal Modeling】-Effect of Maca Extract on Toxicity and Immune Organs of Mice

To investigate the effects of maca extract on the toxicity and immune organs of mice...

2022-09-30

【Animal Modeling】-Behavioral Detection and Analysis of Rncat Mice with Congenital Cataract

To detect and analyze the behavioral changes of Rncat mice with congenital cataract...

2022-09-30

【Animal modeling】-Effect of curcumin pretreatment on myocardial oxidative stress and apoptosis in rats with heat stroke in dry heat environment

To observe the effects of curcumin pretreatment on myocardial oxidative stress and apoptosis in rats with heat stroke in a dry heat environment and explore its possible mechanism...

2022-09-30

【Animal modeling】-Tissue distribution of sialic acid receptors in dogs and susceptibility to H3N2 subtype canine influenza virus

To determine the type and distribution of influenza virus receptors in different tissues and organs of dogs, and to verify the susceptibility of dogs to H3N2 subtype canine influenza virus...

2022-09-30

【Animal modeling】-The expression changes and effects of BDNF and its receptor TrkB in hypoxia-preconditioned mice

To explore the expression changes and effects of BDNF, TrkB receptor and BDNF/TrkB signaling pathway in acute hypoxia and hypoxia preconditioning mice, to further improve the molecular mechanism of hypoxia preconditioning neuroprotection, and to prov...

2022-09-30

【Animal Modeling】-Mechanism of Aspirin on the Control of Salt-Sensitive Hypertension in Rats

To investigate the regulatory effect and related mechanism of aspirin on salt-sensitive hypertension in rats...

2022-09-30

【Animal Modeling】-Mesenchymal stem cell-derived exosomes regulate cardiac autophagy through microRNA-21-5p and affect cardiac function in rats with myocardial ischemia

To investigate whether exosomes secreted by mesenchymal stem cells regulate cardiac autophagy through miR-21-5p and affect cardiac function in rats with myocardial ischemia...

2022-09-30

【Animal Modeling】-Myocardial tissue-specific Isca1 knockout causes abnormal cardiac structure in neonatal rats

To explore the effect of myocardial tissue-specific Isca1 knockout on rat heart structure by magnetic resonance analysis and pathological analysis of myocardial tissue-specific Isca1 knockout rats...

2022-09-30

【Animal Modeling】-Expression of Transient Receptor Potential Channel 1 in Ozone-induced Lung Tissue Inflammation in Mice

To investigate the expression of canonical transient receptor potential channel 1 (TRPC1) in mouse lung tissue under ozone exposure...

2022-09-30

【Animal Modeling】-Scientists try to use young blood to regenerate aging tissues in animal experiments

Xenosymbiosis is a 150-year-old surgical technique that connects the vasculature of two living animals. It mimics natural instances of shared blood supply, such as conjoined twins or animals sharing the same placenta in the womb...

2022-09-30

【Animal Modeling】-Types of β-amyloid and the Pathogenesis Model of Alzheimer

Inoculation of mice with brain homogenates from sporadic Alzheimer\\\'s disease patients elicited cerebral amyloid deposition in recipients, suggesting that the amyloid beta (Aβ) peptide may self-proliferate as a prion...

2022-09-30

【Animal modeling】-Effect of rosuvastatin on myocardial matrix metalloproteins and inflammatory factors in rats with acute myocardial infarction

To observe the changes of matrix metalloproteinase MMPs, TIMP2 and inflammatory factors TNF-α and IL-1β in myocardial tissue of rats with acute myocardial infarction (AMI) treated with rosuvastatin...

2022-09-30

【Animal Modeling】-Why do rodents in arid areas have high drug resistance?

Recently, the innovation team of grassland pest and rodent monitoring and prevention and control of the Institute of Plant Protection, Chinese Academy of Agricultural Sciences, by comparing the molecular evolution characteristics of drug resistance-r...

2022-09-30

【Animal Modeling】-Expression of NF-κB in Hepatocytes of Rats with Welfare Injury Induced by Braking

To study the expression changes of NF-κB in hepatocytes of rats with welfare injury induced by immobilization...

2022-09-30

【Animal Modeling】-CBA/CaJ Mice Organ Weight, Blood Physiological and Biochemical Indexes and Immune Cell Proportion

To determine the basic biological indicators of SPF CBA/CaJ mice, and to lay a foundation for better use of this strain of mice for biomedical research...

2022-09-30