【Animal Modeling】-Effect of Body Weight Fluctuation on Blood Glucose Levels in Mice

To observe the regular characteristics of changes in blood sugar levels affected by weight gain and loss...

2022-09-29

【Animal modeling】-Observation of multimodal molecular functional imaging of female rhesus monkey kidneys at different ages

To observe various imaging indexes such as GFR, ADC, SUV, CT value of female rhesus monkey kidney in different age groups, and to explore the effect of age on various imaging quantitative indexes of female rhesus monkey kidney...

2022-09-29

【Animal Modeling】-Expression of BDNF, trkB and ChAT mRNA and protein in the brain of adult Chinese shrew

To observe the mRNA and protein expressions of BDNF, trkB and ChAT in the brains of adult Chinese shrew...

2022-09-29

【Animal Modeling】-Comparison of two different reagents for the four detection results of hemagglutination in SD rats

To compare the four-item (PT, APTT, TT, FIB) detection results of hemagglutination reagents (PT, APTT, TT, FIB) in experimental animals SD rats and humans with two different brands of hemagglutination reagents imported and domestic to observe whether...

2022-09-29

[Animal modeling] - Effect of Oct4 and Cdx2 on differentiation of bovine embryo inner cell mass and trophoblast

To study the effect of Oct4 and Cdx2 knockdown on the gene expression related to the differentiation of bovine ICM and TE, and to explain the role of Oct4 and Cdx2 in the early development of bovine embryos...

2022-09-28

[Animal modeling] - Tanshinone IIA's neuroprotective effect on Alzheimer's disease model mice and its effect on PI3K/AKT pathway

To investigate the neuroprotective effect of tanshinone IIA (Tan IIA) on Alzheimer\'s disease (AD) model mice and its effect on phosphatidylinositol-3-kinase/protein kinase B (PI3K/AKT) pathway...

2022-09-28

[Animal modeling] - Explore the molecular mechanism of resveratrol against myocardial ischemia-reperfusion injury in rats based on network pharmacology

To explore the effect of resveratrol on myocardial ischemia reperfusion injury in rats and its mechanism in vivo based on the screening method of network pharmacological information...

2022-09-28

[Animal modeling] - Spirillum hepatica infection promotes the development of nonalcoholic fatty liver disease in mice induced by high-fat diet

To investigate the effect of Spirillum hepaticum infection on nonalcoholic fatty liver disease induced by high-fat diet...

2022-09-28

[Animal modeling] - Observation on the effect of Lumianning Ⅱ and ketamine combined with propofol on the experimental pigs undergoing endoscopic surgery via natural cavity

To observe the anesthetic effect of induced anesthetics Lumianning Ⅱ or ketamine combined with propofol on experimental pigs undergoing the placement of gastric gallbladder stent for bile conservation and lithotomy through the natural lumen endoscopi...

2022-09-28

[Animal modeling] - The role of villin 1 in the model of unilateral nephrectomy Habu nephritis in mice

To investigate the similarities and differences between unilateral nephrectomy (UNX) mouse Habu nephritis model and normal mouse Habu nephritis model in renal function, renal pathology and expression of glomerular villin 1 (VIL 1) and their molecular...

2022-09-28

[Animal modeling] - alprostadil on eIF2 of rats with fulminant liver failure α/ Effects of ATF4/CHOP pathway on liver function

To investigate the effect of prostaglandin e 1 (PGE1) on liver function in rats with fulminant liver failure (FHF) and its effect on eukaryotic translation initiation factor 2 α (eIF2 α) / Activates the regulation of the transcription factor 4 (ATF4)...

2022-09-28

[animal modeling] - effect of salidroside on Nrf2 / Keap1 signaling pathway and wound healing in diabetes foot ulcer rats

To investigate the effect of salidroside (Sal) on nuclear transcription factor E2-related factor 2 / Kelch-like epichlorohydrin-related protein 1 (Nrf2 / Keap1) signaling pathway and wound healing in diabetic foot ulcer (DFU) rats...

2022-09-28

【Animal Modeling】-Regulatory effects of corstine on skin inflammation and autophagy in psoriasis mice by inhibiting C5a/C5aR1 pathway

To investigate the regulatory effect of Cosentyx on skin inflammation and autophagy in psoriatic mice through the C5a/C5aR1 pathway through the imiquimod (IMQ) mouse model of psoriasis...

2022-09-28

【Animal Modeling】-Effect of Qingre Runzao Oral Liquid on the upstream and downstream cytokines of ILC2s in asthmatic mice

To intervene ovalbumin (OVA)-sensitized asthmatic mice with Qingre Runzao Oral Liquid, and to observe its effect on the number of type II innate lymphocytes (ILC2s) and its upstream and downstream cytokines in asthmatic mice...

2022-09-28

【Animal modeling】-Intervention effect and mechanism of Exendin-4 on STZ-induced diabetic nephropathy in rats

To study the intervention effect and possible mechanism of Exendin-4 on streptozotocin-induced diabetic nephropathy in rats...

2022-09-28

【Animal Modeling】-Research on the analgesic effects of Lugai Qishan Fluoxane on labor and delivery based on MAPK signaling hypoxia

To investigate the effect of sevoflurane labor analgesia on hypoxia in neonatal rats based on the mitogen-activated protein kinase (MAPK) signaling pathway...

2022-09-28