The development of human diseases is very complex. Taking human beings as the experimental object to deeply explore the mechanism of disease occurrence and promote the development of medicine is slow. The experience accumulated in clinical practice is not only limited in time and space, but also limited in morality and methods in many experiments. With the help of indirect research on animal models, we can consciously change those factors that are impossible or difficult to eliminate under natural conditions, so as to more accurately observe the experimental results of the model, and carry out comparative research with human diseases, which is conducive to more convenient and more effective understanding of the occurrence and development of human diseases and research on prevention and control measures. It is not easy to establish a disease membrane type that is equivalent to human disease status. Various model animals are quite different from humans in terms of gene level, living habits, microbial composition in vivo, etc. The proximity of disease models to real diseases determines the accuracy of disease biological research and drug detection.
Our company has SPF level animal experimental platform, which can independently complete rat and rat inflammatory models, autoimmune disease animal models, liver and metabolic disease animal models The construction of conventional models such as orthopedic disease animal models and tumor animal models (such as nude mice transplanted tumor, common mice bearing tumor, tumor metastasis animal models, etc.), as well as various subsequent behavioral tests (including water maze test, open field test, forced swimming test, tail suspension test, treadmill test, etc.) and various pathological tests; In addition, our company also acts as an agent for various gene editing animal models.
Note: For the animal modeling project that does not belong to the conventional model, the detailed scheme shall be provided.
Grade and cleanliness of laboratory animals
Common animals (CV): experimental animals with the lowest requirements for microbial and parasite control;
Clean animals (CL): eliminate the pathogens of zoonoses and major infectious diseases of animals;
Animals without special pathogens (SPF): on the basis of clean animals, animals are required not to carry specific microorganisms and parasites that may interfere with the conduct or results of the experiment according to the needs of the experiment;
Service process
Customer online order - order/experimental material confirmation - animal feeding - model construction - result delivery
Service Content and Description
Applicable scope
Animal disease models are mainly used for research in experimental physiology, experimental pathology, and experimental therapy (including new drug screening). The details are as follows:
