动物实验 z-bo 2020-08-28 406

　　It treats diseases through external electrical stimulation, collects nerve electrical signals, and detects neurofeedback to external stimulation. The stimulation, reception, collection, transmission of neuroelectric signals and the development of corresponding signal analysis equipment are hot topics in clinical medicine, biomedicine and electronic technology. The results of nerve electrical stimulation and nerve electrical signal analysis are widely used in clinical medicine such as disease analysis, treatment and monitoring, and the performance requirements of related stimulation and signal detection modules are constantly improving.

　　Deep Brain Stimulation (DBS) is an effective treatment for a variety of neuropsychiatric diseases, including Parkinson's disease (PD), essential tremor (primary tremor) and primary encephalitis. Dystonia (primary dystonia) etc. In 1987, Bena Verde discovered that high-frequency electrical stimulation can destroy the ventral intermediate nucleus (VIM) of the thalamus, but it can improve symptoms such as tremor. Because electrical stimulation is reversible, programmable, and can be performed on both sides of the brain, this innovative therapy quickly gained popularity. This is the origin of brain electrical stimulation therapy or deep brain electrical stimulation.

　　DBS treatment method mainly uses stereotactic technology and microelectrode recording technology to insert electrodes into specific nuclei of the brain, and uses continuous high-frequency pulse electrical stimulation to inhibit abnormal brain nucleus discharge to achieve the therapeutic effect. Is achieved. Microelectrodes record electrical nerve signals.