动物实验,糖尿病 z-bo 2020-08-31 444

　　Previous reports have shown that the innate immune cells of non-obese diabetic mice are defective, and the Toll-like receptor TLR4 plays a role in preventing type I diabetes. Williamidgway, chair of the Department of Immunology, Allergy and Rheumatology at the University of Cincinnati, said his research team used the monoclonal antibody UT18 to enhance TLR4 activity and help people with new diabetes develop diabetes. Said to have overthrown most. Diabetes is newly developed in obese mice.

　　Satokiyin: "Our research shows that using antibodies to stimulate specific molecules in the innate immune system can trigger new diabetes in mice that have already developed diabetic symptoms. It can be reversed and has a high success rate. The reason for the success of this reversal It is because the beta cells of the pancreas are preserved in autoimmune attacks. He said that the key to reversing diabetes is to stop the disease usually in a short period of onset. Although the body has a long onset, it is from a new onset to the end of type I diabetes. The time is still relatively short.