【Animal Experiment】-Researchers have verified that Alzheimer's disease comorbid cerebrovascular disease can aggravate disease symptoms through mouse models

  New research shows that both Alzheimer's disease and cerebrovascular disease can exacerbate the symptoms of the disease. Recently, two research groups have simultaneously studied this problem and verified this conclusion from various aspects through the mouse model.

  The work of

  Murphy and his team combined effects on mouse models of type 2 diabetes, Alzheimer's disease and cerebrovascular disease. Wilcock and her team also studied the role of Alzheimer's disease and hyperhomocysteinemia in mouse models. Homocysteine levels are associated with many diseases, including cerebrovascular diseases.

  The research of the two teams came to similar conclusions. Although the main pathological features of Alzheimer's disease remain unchanged, the patient's learning ability and memory are even significantly reduced. In mouse model studies, the simultaneous development of Alzheimer's disease and cerebrovascular disease will increase the severity of the disease. The results of these studies can explain why 40% of Alzheimer's disease patients still suffer from cerebrovascular disease, and may be useful for the treatment of future diseases.