动物实验 z-bo 2020-09-01 417

　　In mouse experiments, the insulin produced after feeding is essential for rebuilding the chaotic biological clock, and food may be a new weapon to alleviate jet lag. Miho Sato of the Time Institute of Yamaguchi University in Japan and his colleagues conducted experiments on mouse and tissue culture, and for the first time found that increased insulin affects the circadian rhythm. This rhythm affects wake and sleep patterns and regulates many other physiological processes. Miho Sato demonstrated the role of insulin by feeding mice only at night and changing the liver's biological clock.

　　Then, the researchers divided the mice into two groups, suppressed insulin levels in one group of mice, and then modified them to feed the two groups of mice during the day. Four days later, the biological clock in the liver of mice that did not inhibit insulin levels returned to normal rhythm, but the biological clock in the liver of mice that did not inhibit insulin levels still did not return to normal.

　　If the body's biological clock is similar to the rat's biological clock, Sato Miho's research shows that those with jet lag can adjust their diet to speed up the recovery of the biological clock.. "During jet lag, our body may adjust itself very slowly. But we can use it. The conclusion of the study. When flying from London to Japan, we will have a time difference of 8 hours. Biologist Urs Albrecht of the University of Fribourg in Switzerland said that this may be vague, we It was learned from experiments on mice in the early morning. In the orchestra of the human body, every cell has a running clock. Although the suprachiasmatic nucleus of the brain is the commander of the zone, the environmental signals of food will also affect The circadian rhythm of the entire human body."