[Animal Experiment]-Scientists extend the preservation time of rat liver for transplantation

  Thanks to the efforts of scientists, the preservation and preservation period of rat liver used for organ transplantation has been significantly extended to 4 days. A study published in "Natural Medicine" found that it may directly solve the current crisis of insufficient human organ donation.

  Due to current organ storage restrictions, human organs can only be stored for 6 to 12 hours. Extending the storage time of human organs may have a significant impact on clinical cases of liver transplantation. Physicians will have more time to actively prepare recipients for organ transplantation, and at the same time provide a wider source of donated organs from a geographical perspective. Korkut Uygun and his colleagues combined in vitro machine perfusion and methods based on non-frozen (or ultra-cold) tissue preservation methods, and transplanted rats one month after the liver was preserved for three days. Facts have proved that the survival rate can reach 100%.

  The survival rate of liver transplantation rats stored for 4 days can reach 60% in the next month. In contrast, all rat livers preserved for 3 days using traditional methods are necrotic and cannot be used.