动物实验,动物研究 z-bo 2020-09-02 445

　　Exercise is not only for weight loss. New animal studies show that exercise can also improve bone thickness, increase bone strength and reduce bone obesity.

　　Our bone marrow contains fat.

　　TheMouse study also provides potentially good news for weight loss. During running, fat cells in the bone marrow of lean obese mice decreased. However, the number of fat cells in the bones of obese mice was significantly reduced. Exercise can strengthen bones It is well known that exercise in obese mice seems to strengthen bones. Exercise is associated with increased bone mass in lean obese mice.

　　The researchers recalled that the results of this study still exist, and people have not seen it yet, because "mouse research cannot be directly translated into a human state."

　　The types of stem cells that produce bone and fat in mice are the same as the types of stem cells that produce bone and fat in humans. So far, researchers have believed that bone marrow fat is different from other types of body fat and is not used as an energy source during exercise.

　　But new research shows that this may not be the case. The scientists studied two groups of mice: 14 lean mice on a "normal diet" and 14 obese mice on a high-fat diet. At twelve months, half-obese and half-lean mice were provided with treadmills. After six weeks, bone measurements showed that about 20% of running mice had high bone density. In all mice that exercise normally, the size of fat cells is also significantly reduced. However, the number of fat cells contained in the bones of lean mice did not change. Compared with obese mice that did not exercise, mice that lost more than half of their fat cells during running were obese mice.. In terms of improving bone strength, Running is more pronounced in obese mice.

　　But the "basic physiology" behind fat storage is not well understood. What are the disadvantages of exercise on bone fat?

　　The current focus of researchers is to continue animal research. But the research team says that these studies may ultimately point to ways to maintain and improve bone health in patients with diabetes, arthritis, anorexia, and long-term use of steroids.

　　However, the skeletal behavior of rodents is different from that of humans, and in normal growth, the metabolic behavior of mouse bones is significantly different from that of humans. We should work hard to explore people's bone fat dynamics.