动物实验,椎间盘脱出 z-bo 2020-09-04 403

　　Objective: To study the repair effect of electroacupuncture on spinal cord injury in dogs with intervertebral disc herniation and its effect on somatosensory evoked potentials.

　　Method: Divide beagles into three groups randomly. Use the model group and the electro-acupuncture group to create a model of intervertebral disc herniation with balloon compression. Electroacupuncture was performed every day after surgery. The control group received sham surgery. Before surgery (0d) and 1, 4, 7 and 14 days after surgery, each dog was scored using the Texas Spinal Cord Injury Scale (TSCIS) scoring method. The SEP was measured with an electromyogram induced electrometer, and its latency and amplitude were analyzed.

　　Results: On the first day after operation, the TSCIS scores of the model group and the electroacupuncture group were significantly lower than those of the control group (P\u003c0.01), and the difference between the electroacupuncture group and the model group was significant 14 days after the operation (P\u003c0.01) ); The SEP latency of the model group and the electroacupuncture group was higher than that of the electroacupuncture group 4 days after the operation (P\u003c0.05) The latency of the electroacupuncture group and the model group was significantly shortened, 14 days after the operation, and 1 day after the operation. Sexual difference (P\u003c0.05). The SEP amplitudes of the model group and the electroacupuncture group were significantly lower than those of the control group (P\u003c0.05). On the 14th day after surgery, there was a significant difference in amplitude between the electroacupuncture group and the model group (P\u003c0.05).

　　Conclusion: Electroacupuncture can effectively promote the repair of spinal cord injury in dogs with intervertebral disc herniation, improve TSCIS score, restore SEP waveform, shorten the incubation period and increase the amplitude. Yes; SEP reflects the degree of spinal cord injury to a certain extent, and can evaluate the effectiveness of electroacupuncture Sex.