【Animal Modeling】-Reducing calorie intake helps Japanese lemurs live longer

  According to a report by the French media "European Scientist", Brunovas's "Adaptive Evolution Mechanism" laboratory in Essonne, France, recently reported that it has strictly controlled calorie intake and that it can greatly extend the lifespan of Japanese lemurs.

  The research over the past ten years was jointly conducted by the French Scientific Research Center and the Natural History Museum. The subjects of the study are two groups of Japanese lemurs. This animal is the smallest primate and has a "distant relationship" with humans. For a long time, a group of Japanese lemurs has been dominated by adult calories. Compared with other normal diet partners, calorie intake has been reduced by 30%.

  According to research, reducing calorie intake by 30% is within the acceptable range of Japanese lemurs, without pain, and without reducing daytime activities. Metabolism can adapt to this limitation. In addition, this "compulsory diet" has a positive effect on the average life span of Japanese lemurs. Researchers have observed that Japanese lemurs at a severe eating age are slower, exhibiting some characteristics of young Japanese lemurs, and life expectancy has increased by 50%. In particular, in this study, the average life span of Japanese lemurs on a normal diet was 6.4 years, half of the Japanese lemurs were younger than 6.4 years, and the average life span of the calorie-controlled Japanese lemur group was 6.4 years. The age of 9.6 years is already the "old age" of this creature.

  This research also supports the conclusion drawn by observing some short-lived animals (ears, flies, mice, etc.) in the past. Fabiennes Aujar, a researcher at the French National Center for Scientific Research, said that scientists have been studying mice since the 1930s. longevity. However, this is the first study of animals that have many similarities with human performance. As she pointed out, the research finally proved that diet-controlled lemurs are younger and live longer than normal diet lemurs. There are still some uncontrollable factors. To study how calorie control slows down aging and prolongs life, we need to understand the physiological changes in long-term calorie intake.