【Animal Modeling】-Research on a learning and memory evaluation method based on animal spontaneous behavior

  Purpose: To discuss the experimental procedures and evaluation indicators in the four modes of object recognition experiment, object recognition experiment, and object position recognition experiment? Provide research methods. Mode, delicate and sensitive behavioral experiment method.

  Method: Two mouse strains, KM and ICR, were selected, and four experimental models were used to study the test period, adaptation period and interval time. Results: In the four experimental modes, the familiarization period is 5 minutes, the interval between the familiarization period and the test period is 10 minutes, and the test period is 3-5 minutes, which can better evaluate the animal's memory ability.

  Conclusion: The research system clarified the four modes of object cognition, the development mechanism of learning and memory impairment, and the detection steps, intervals and indicators of object cognition used in the development of new drugs and health products. It provides a stable, reliable and standardized method.