动物实验 z-bo 2020-07-20 841

Animal studies have found that morning exercise can improve metabolic response and evening exercise can increase energy expenditure

　　The circadian rhythm is an internal process of the human body that circulates every day. This rhythm usually responds to the light level in the personal environment, which helps regulate the sleep-wake cycle. Maintaining a consistent circadian rhythm is essential to overall health-long-term disruption of your regular sleep schedule may adversely affect your health. Now, recent research has discovered new ways in which circadian rhythms affect your health.

　　A study published in the journal Cell Metabolism found that healthy circadian rhythms and the time of day affect the effects of aerobic exercise on metabolism. Studies have shown that morning exercises can make muscle cells more easily metabolize sugar and fat, while evening exercises can make you fully promote metabolism for a longer period of time.

"There seems to be a considerable difference between the effects of exercise performed in the morning and in the evening. These differences may be controlled by the body's biological clock. Morning exercises activate genetic programs in muscle cells to make them more effective and metabolize sugar and fat. On the other hand, evening sports will increase the body’s energy expenditure,” said Jonas Thue Treebak of the Novo Nordisk Fundamental Metabolism Research Foundation.

　　 is like day and night

　　 From a researcher at the University of Copenhagen-in collaboration with the University of California, Irvine-looked to understand the impact of exercise performed at different times of the day. To test their theory, Treebak and his colleagues let a group of rodents exercise at the beginning and end of the day. Afterwards, they analyzed the effects of exercise on rodent muscle cells.

　　Researchers used high-throughput transcriptomics and metabolomics methods to discover very different responses to metabolic vibrations, which are characteristic of exercise during the day or night. It is worth noting that the researchers discovered that a protein called hypoxia-inducible factor 1-α (HIF1-alfa) is involved in these mechanisms, which is responsible for regulating the body's biological clock. The research team explained that when you exercise, certain proteins are selectively activated, depending on the time of day. This selective activation leads to the use of alternative energy sources, adaptation of energy consumption and consumption of carbohydrates. (Related: Fitness and your circadian rhythm: Is jogging at night better than walking in the morning?)

　　 Their findings indicate that early morning exercise can increase the ability of muscle cells to metabolize fat and sugar-this discovery may arouse researchers' interest in patients with type 2 diabetes and severe obesity.

　　 On the other hand, exercising at night can increase the body's energy expenditure within a few hours after a long period of good exercise. This means that researchers cannot confidently conclude that morning exercise is much better than evening exercise.

"On this basis, we cannot determine whether it is best to exercise in the morning or at night. At this point, we can only conclude that the effects of the two seem to be different. Of course, we must do more work to determine The underlying mechanism of the beneficial effects of exercise training at these two time points. We are eager to extend these studies to humans to determine whether regular exercise can be used as a treatment strategy for patients with metabolic diseases.” Treebak explained.

　　 Whether you decide to go for a morning jog or save it later in the day, if you exercise regularly, it will eventually bring many health benefits. FightObesity.news provides everything you need for the health benefits of exercise and other natural means to improve overall health.