[Animal Modeling] Effect of 4-week ladder resistance training on hypoxia-induced skeletal muscle atrophy in rats

  Objective: To study the impact of resistance training on skeletal muscle atrophy caused by hypoxia, and to provide a theoretical basis for solving the problem of skeletal muscle loss in athletes during advanced training.

  Method: Twenty-four male Sprague Dawley (SD) rats, an average of 8 weeks, weighing about 230 g, were randomly divided into 4 groups. With the normoxic quiet group (C), normoxic resistance training group (R), hypoxic quiet group (H) and hypoxic resistance training group (HR) in the HR group, I did resistance at a simulated altitude of 4000m in the H and HR groups training. After four weeks of intervention with hypoxia and resistance training, we tested the body composition of each group of rats, including soleus, extensor digitorum longus, gastrocnemius and biceps. Wet weight and muscle fiber cross section?

  Result: The lean body mass of the HR group was significantly higher than that of the H group, while the lean body mass of the H group was significantly lower than that of the C group; biceps wet weight and muscle fiber loss in the HR group. The area of group H is significantly higher?

  Conclusion: Resistance training helps prevent skeletal muscle atrophy caused by hypoxia. Will resistance exercise in the form of a ladder stimulate biceps hypertrophy in rats?