食物纤维,心脏健康 z-bo 2020-09-09 506

　　The clues come from various microorganisms in the gut. These kids help to process food, especially fiber. Perhaps some beneficial microorganisms have transformed the indigestible plant fiber to some extent into substances that are beneficial to the health of the "body" and "mind and mind", but this relationship is still uncertain. Researchers at the University of Wisconsin-Madison confirmed that the mouse model of a high-fiber diet has a special fatty acid protection mechanism. Certain bacteria produce this fatty acid called butyric acid when digesting plant fiber. Scientists say that mice with high-butyric acid-producing bacteria have less atherosclerosis and inflammation after eating high-fiber foods than mice without bacteria, but mice with roseic acid bacteria have lower levels. Fiber-fed mice are not protected. Because there is no fiber, the bacteria will produce very low butyric acid.

　　The results of this research were published in "Nature Microbiology" in collaboration with researchers from the University of California, Los Angeles (UCLA) and Goethe University, Sweden, by Dr. Federicoray, Professor of Bacteriology and his postdoctoral researcher Kazuyuki Kasahara. on. ei said: "Atherosclerosis was once considered a fat metabolism disorder." "Clinical methods to control this disease usually focus on lowering cholesterol and other fats in the blood. But with the development of science, it has been corrected. It is a chronic inflammatory disease.” This may be the key to reducing systemic inflammation (especially inflammation in the blood) to reduce atherosclerosis. Part of the reduction in inflammation depends on the strong intestinal wall. Asa said: "The important function of the intestine is to maintain a friendly relationship with bacteria." When beneficial bacteria release inflammatory molecules and enter the blood through the intestine, they can cause widespread inflammation. In order to keep these molecules in a safe area, healthy intestinal cells form a strong and complete barrier to each other, but the adhesion between intestinal cells is destroyed.

　　"As the cells divide, the intestines will leak more and more," ei said. Kasahara said: "Leakage leads to more inflammation."

　　In order to study the effects of butyrate on the intestinal tract and atherosclerosis, "bacteria with or without Rosbergia are sterile in a specific bacterial community." I treat mice. These mice were fed a diet rich or lacking in dietary fiber. Researchers have found that mice carrying rose hips have lower levels of certain inflammation markers and lower levels of atherosclerosis, but the premise is that you must eat high-fiber foods. If you don’t eat high-fiber foods, rose gummy The content will suddenly drop, causing the mice to lose protection. Researchers have built a mouse model of atherosclerosis through genetic engineering (because mice cannot develop this disease naturally). To determine the link between butyrate and the protection provided by the Roseburia bacteria, the researchers fed mice that orally produce butyrate directly to mice without butyrate. Since pure butyric acid is easily absorbed in the upper gastrointestinal tract, the researchers kept the mice in a slow-release state to keep them intact near the lower gastrointestinal tract.

　　Slow-release butyric acid can reduce fatty spots in transgenic mice by one-third, reduce atherosclerotic inflammation and other markers. Butyric acid can help mice resist atherosclerosis. It is proved that rose jelly can help this The main component of this hardening. according to

　　'S previous work, patients with cardiovascular disease have lower levels of butyric acid producing bacteria (such as rose hips). This research reveals for the first time a clear connection between dietary fiber, microbes and health. But the researchers warn that the results of this study do not mean that butyric acid is a new simple heart health supplement, and natural dietary fiber is still an ideal way to support intestinal health. method.

　　Ay said that years of research have made him a lot of money from eating natural fiber. "My wife makes oatmeal every morning. The bread my family buys is high-fiber whole grain bread made from malt."