动物造模,糖尿病 z-bo 2020-09-09 372

　　Objective: How to observe the effect of maca combined with exercise therapy on the activity of mitochondrial respiratory enzymes and renal function in diabetic rats?

　　Method: Randomly divide 40 diabetic rats into model control group, maca group, exercise group and maca + exercise group? Do the Maca and Maca + exercise groups take Maca powder (5g/kg) every day? Do exercise and Maca+ exercise groups receive treadmill training? After 6 weeks, each group of rats performed a lot of exercise (35 m/min), and then immediately anesthetized the kidney mitochondria and mitochondrial respiratory chain enzyme RCCI? CCII? CCIII? CCIV activity and blood urea nitrogen (BUN)? Serum creatinine (SCr)? Do you extract blood sugar (blood sugar) content?

　　Result: Compared with the control group, how about the mitochondrial respiratory chain enzyme RCCII and RCCI in the kidney of the exercise group? RCCII and RCCI for Maca+ sports group? CCII? Compared with the maca group, the RCCIV activity of the maca group was significantly increased. + Practice group RCCI? CCII activity increased significantly; Maca + exercise group RCCII activity increased significantly compared to exercise group? Compared with the control group, the maca group? The blood urea nitrogen content of rats in the Maca + exercise group, the serum creatinine and blood sugar levels of the exercise group Maca + exercise group decreased, and the difference was statistically significant (P\u003c0.05 or P\u003c0.01); Maca Maca + exercise group Serum creatinine and blood glucose levels were lower than those of the control group, and the difference was statistically significant (P\u003c0.05); the Maca + exercise group had higher urea nitrogen and blood sugar levels than the exercise group. Is it reduced and the difference is significant (P\u003c0.05)?

　　Conclusion: Can the combination of Maca and exercise therapy improve the renal function of elderly diabetic rats, enhance respiratory function, increase the level of oxidative phosphorylation in the body and improve renal function?