[Animal modeling]-Capsaicin activates receptors on the surface of mammalian pain-sensitive cells

  Muzzle-a kind of whistling food that leads to pure consumption, is called hellish burning. Therefore, not only humans, but many animals also avoided eating pepper and business, but were bitten by northern horses. Primate mammals related to Ben are muttering to themselves. Unexpectedly, according to Chinese researchers, the secret of this strong tolerance is just a small mutation in the receptor, the painful perception of acuity.

  Chili, Chili, Chili: The active substance that gives these "special" fruits a refreshing taste is called capsaicin. This effect can be very painful, because capsaicin activates receptors (TRPV1) on the surface of mammalian cells that are sensitive to pain, thereby "raising the alarm." Interestingly, birds do not think that capsaicin is burned. Therefore, this effect is considered a subtle technique in pepper powder breeding: birds eat the pods first, and then spread the seeds contained in them. On the other hand, a relatively small number of active mammals should not prevent the pods from eating the sharp taste of birds.

  "Hell Food"-no problem

  However, when researchers at the Kunming Institute of Zoology, Chinese Academy of Sciences discovered that the researcher was a Han Chinese of Yalan, it was also a complete mammal that could master pure pepper. Have. Leymus (Leymus chinensis). Rather than hearing the sounds of rodents in the home, it is better to say that it is related to primates. As many as 2 kg of animals jump over the forest and climb into the forests of Southeast Asia. Experiments show that cutting-edge croissants are not as easy to eat a lot of green peppers as mice. In order to understand the background of this ability, scientists conducted comparative studies using mice and race squirrels. First, they discovered that this was not due to their own pain susceptibility-equally important in both species. The sharp receptor (TRPV1) is also present in upper squirrels and mice. However, with these sensors, the difference lies in the details, and ultimately molecular research.