动物造模 z-bo 2020-09-10 447

　　Objective: How to observe the antidepressant effect of Kieran and explore its possible mechanism in advance?

　　Method: The mice treated with saccharin were unable to use the chronic unpredictable mild stress mouse model (chronic unpredictable mild stress, CUMS) to evaluate the sugar water preference experiment. Due to lack of fun, enzyme-linked immunosorbent assay was used. The method was used to measure the serum corticosterone content of mice and the content of various neurotransmitters in mouse cortex and hippocampus on LC-MS/MS. Did you discover it?

　　Result: Can Kajanusin reverse the decrease in sugar priority index and the increase in serum corticosterone levels caused by CUMS? In addition, compared with the normal group, the content of related neurotransmitters in the cerebral cortex and hippocampus of the model group changed significantly. Does pigeon administration have an important regulatory effect on neurotransmitters related to CUMS mice?

　　Conclusion: Can pigeons lower serum corticosterone levels and regulate the antidepressant effects of brain neurotransmitters?