动物造模,动物实验 z-bo 2020-09-10 394

　　Researchers in Berlin, Germany, did not repeat experiments on mouse disease models in the laboratory. Instead, they used Cointos to see if the drug could protect the brain from stroke.

　　Through this provocative and seemingly silly experiment, Sophie Piper of the Berlin Institute of Health (BIH) and Berlin Philanthropy University and colleagues thoroughly explored issues that may affect experimental biomedical research. clarify. Small sample size (usually less than 10), and statistically significant (5%), is almost universally accepted under a moderate threshold, leading to a higher rate of false positive results and overestimating the true effect. Their work provided evidence to researchers. Contrary to popular expectations, research replicated in many laboratories around the world in a common environment proved what can be gained by tossing a coin. Remind me that it might not.

　　Many fields of research suffer from the so-called "copy crisis". The results of one laboratory cannot usually be reproduced by researchers in another laboratory, and the successful recall rate is usually less than 50%. This has shaken confidence in the overall health of the science company and stimulated investigations into the underlying cause. Therefore, many researchers have begun to repeat experiments in the laboratory, which is an integral part of strong science and good scientific practice. However, Piper and colleagues carefully studied the usefulness of replication lab experiments in their article and issued a surprising warning about current replication practices.