动物造模 z-bo 2020-09-10 374

　　American scientists report using an external organ support system to regenerate injured pig lungs. Preliminary results indicate that damaged pig lungs can be repaired and used for organ transplantation.

　　Inhalation of stomach contents refers to the invasion of stomach contents into the airway. This common injury may prevent lung transplantation. Given that the world is facing a shortage of transplant donors, damaged lung regeneration technology is expected to expand the organ bank suitable for human transplantation.

　　This time, Vanderbilt University researcher Matthew Bucketta and his colleagues studied the possibility of regenerating severely damaged lungs to meet transplant standards. The research team used pigs as experimental subjects (the size and shape of internal organs of pigs are similar to human organs and are considered potential donors for organ transplantation), as well as the stomachs of eight pigs. Copy the content inhalation barrier. The external support system connects the injured lung to the circulatory system of the recipient animal to maintain the organs. according to

　　Research, this cross-circulation system can be used to maintain the donor’s lungs outside the pig for 36 hours, allowing a series of therapeutic interventions. This system can not only regenerate the damaged lung, but also improve its function. The regenerated lung can meet all transplant conditions. The researchers said that further studies are needed to determine the safety and methods of functional lung activity after lung transplantation. Since human organ transplantation must receive immunosuppressive treatment, the impact of immunosuppression on lung cancer recovery will be further evaluated in the future before it is used in the medical community to alleviate the shortage of transplantable organs. Need to be completed.