动物造模,动脉阻塞 z-bo 2020-09-10 337

　　Healthy injection of proteins related to healthy lymphatic function can reduce the occlusion of atherosclerosis in mice. According to a preliminary study presented at the American Heart Association's 2019 Vascular Discovery Science Conference, this discovery may one day provide new methods for the prevention and treatment of heart disease and stroke by targeting the lymphatic system.

　　New scientific research in biology, peripheral vascular disease, vascular surgery and functional genomics. Researchers are trying to determine how early protein exposure affects the accumulation of plaque that can lead to heart disease, and whether protein reduces or even prevents blockages. Yes, they found that mice injected with a protein called VEGF-C152S had about 30% fewer arterial plaques than mice that did not receive the protein. Transgenic puppies lacking LDL receptors received four injections per week of the regular diet three times a week.

　　Then, he stopped feeding the rats a high-fat diet for 8 weeks to induce atherosclerosis, and then resumed a normal diet for 4 weeks. Despite eating a high-fat diet for 8 weeks, VEGF-C152S injection can reduce plaque accumulation. In addition, the injected mice have more stable plaques, which can reduce plaque rupture and stroke. The protein VEGF-C152S is related to reducing inflammation and improving lymphatic function. This is also essential for the development of new lymphatic vessels. The researchers pointed out that the lymphatic system is a network of tissues and organs that is usually involved in the process of removing waste from the body and has not been fully studied in atherosclerosis. However, the link between the lymphatic system and the accumulation of cholesterol in the arterial wall may provide new insights. The lead author of the study said: "Our findings show that early targeting of the lymphatic system can inhibit atherosclerosis and even prevent atherosclerosis." Dr. Andrea Mirasan said.

　　Candidate in the laboratory of Dr. Catherine Martel at the Montreal Heart Institute in Montreal, Quebec, Canada. "Lymph affects the removal of cholesterol and inflammatory components attached to arterial walls through body movement. The lymphatic system now has the potential to understand heart health and the development of cardiovascular disease. This is a factor. What you do can protect your blood vessel health.