Parkinson's disease affects millions of people worldwide and is caused by the loss of neurons. Studies have shown that fetal tissue transplantation has shown "talent" in restoring neuron loss, but the reasons and ethical issues of tissue use limit its use.
In a study in the Journal of Clinical Research, Vania Broccoli and other tissues of the San Rafael Institute of Science successfully transformed fibroblasts into neurons and "transplanted" them into the brains of rodents with Parkinson's disease . These nerve cells improve motor function, but are not as effective as transplanted rat fetal tissue. The researchers then used techniques that allow neurons to express artificial proteins (these proteins can regulate the activity of neurons). It has been found that these neurons can restore motor function in almost the same way as the transplanted embryonic tissue.
New research suggests that fibroblasts can be used in cell replacement therapy for Parkinson's disease.