炎症反应,癌症,遗传 z-bo 2020-09-15 356

　　A new study published in Nature Communications shows that scientists at Uppsala University are the first large-scale study of the significance of genetic, clinical and lifestyle factors on the level of protein in the bloodstream. The results of the study show that genetics and lifestyle are the determinants of protein content. This discovery greatly affects the possibility of using more biomarkers to identify diseases.

　　For those individuals suffering from special diseases, biomarkers used to diagnose diseases can better show changes in protein content. For further research on cancer and inflammation, researchers analyzed 92 protein biomarkers in 1,000 healthy individuals used in clinical studies. Researchers at Uppsala University investigated the effects of genetic, clinical and lifestyle factors on blood for the first time. The meaning of the protein content level in the stream. The results of the study show that more than 75% of genetic factors play an important role in protein. A detailed genetic analysis shows that every 16 genes have a strong protein content level.

　　"These findings are important because they show which variables are important in the changes in measurable values. If these factors are known, we are more likely to see some changes, and we are increasing values and normal values. There will be a clearer breakpoint. Expansion may lead to the use of more clinical biomarkers.” Stefan Enroth explained. He is a researcher in Immunology, Genetics and Pathology at Uppsala University.

　　According to this study, under certain circumstances, more than 50% of the protein content of healthy individuals changes under the combined effect of genetics and lifestyle. This means that for protein biomarkers to be used more effectively, genetic and lifestyle factors must be taken into account.