For a long time, brain diseases like Alzheimer's disease have been an insurmountable problem in the medical profession. People's understanding of these diseases is not as good as cancer and other diseases.
Previously, people equated Alzheimer's disease with the symptoms of amyloid in the brain of patients, but a recent study published in "Nature Neuroscience" showed that there may be a type of beta-amyloid in the brain. Has been completed. The interruption of the compensation mechanism also delays the appearance of Alzheimer's disease symptoms in some patients with β-amyloid in the brain.
Researchers at the University of California, Berkeley used fMRI technology to study 22 young people, 16 old people with beta amyloid in their brains but no forgetting symptoms, and 33 healthy old people. I analyzed the brain data. When beta amyloid appeared in the brains of these 16 elderly people, it was found that the blood flow in the brain exceeded the normal value. In addition, memory tests conducted on these volunteers found that certain parts of the brain of volunteers with beta-amyloid were more excited than healthy people. All these results indicate that the brain has a compensation mechanism to solve the problem of beta amyloid. Researchers say the findings help explain why some older people have beta-amyloid in their brains but do not have symptoms of Alzheimer's disease. It also helps to understand the cause of Alzheimer's disease and drug development in detail.