【Animal Modeling】-Influenza virus and climate factor model construction research progresses

  The results show that the outbreak and spread of influenza viruses are related to climate factors such as temperature and humidity. Time-space analysis shows that H5N1 infection cases are mainly concentrated in southern, central and northwestern China, while H7N9 infection cases are mainly concentrated in eastern and southern coastal areas. H5N1 influenza virus infections were mainly concentrated in the three months of December, January and February, but there was no significant difference in the monthly distribution of H7N9. In addition to the differences in temporal and spatial characteristics, the suitable climate factors for the two viruses are also different.

  The suitable temperature for H5N1 infection is 5-10°C and the wind speed is 1-2 km/h. The suitable temperature for H7N9 is 10-15°C and the wind speed is 2-3km/h. The appropriate humidity for the other two strains is 60-80%. .. Analyzing the human infection of two highly pathogenic avian influenza viruses by integrating climatic factors provides a favorable basis for predicting disease outbreaks and formulating preventive measures. The research expands the basic understanding of the relationship between climate change and human diseases, revealing the thresholds of climate factors affecting human diseases and the dynamic time and space of climate change affecting infectious diseases. We will clarify the mechanism of propagation and evolution. The study also investigated the direct and indirect effects of climate change on the idiopathic effects of typical infectious diseases, and revealed the mechanisms by which climate change affects the spread of infectious diseases.