病毒抵抗力 z-bo 2020-09-23 397

　　A study released by the University of Cambridge in the United Kingdom showed that the human body's resistance to viral infections will change significantly at different times of the day. This is mainly because the human body clock affects the ability of the virus to replicate and spread.

　　They said that when a virus invades the human body, it will "hijack" various operating mechanisms and resources in the cell, thereby rapidly replicating and spreading in the human body. However, under the regulation of the biological clock, the amount of these resources will fluctuate greatly at different times, which will have an impact on virus-related activities. The biological clock regulates many physiological functions of the human body, including sleep regularity, body temperature, immune system, and hormone secretion. The biological clock is related to many genes such as Bmall.

　　To verify this theory, the team observed in the laboratory the reaction of mice infected with the herpes virus at different times of the day. They found that if mice were infected with the virus in the morning, the level of virus replication in their bodies was 10 times that of mice that were infected only 10 hours later that day. The researchers then repeated the same experiment in mice with the Bmall gene removed. The results show that no matter what time of day the mice are infected with the virus, the virus replication is at a very high level, which shows the influence of the biological clock in it.

　　According to this report published in the Proceedings of the National Academy of Sciences in the United States, researchers have also observed that in the cells cultured in the laboratory, the level of virus replication will vary greatly at different times without the intervention of the immune system. Researchers say that if the biological clock in the cell is destroyed, the infection of the herpes virus and influenza A virus will increase.

　　Another author, Cambridge University scholar Rachel Edgar said that there is a biological clock in every cell in the human body. Their research shows that the biological clock of the cell plays an important role in the successful replication of the virus. When blocking mice or When the biological clock in the cells cultured in the laboratory, they found that the degree of virus infection is no longer affected by the time period, and the virus can always maintain a high level of replication.

　　Edgar said that shift workers often have to work day and night upside down, disrupting their biological clock, which is probably an important factor in their ability to resist the virus.