动物实验,神经内分泌调控 z-bo 2020-09-28 460

　　Scholars from the Institute of Hydrobiology, Chinese Academy of Sciences and the School of Life Sciences, Chinese Academy of Sciences jointly published a review article entitled "Neural Regulation of Fish Growth" in the journal "Chinese Science". This article summarizes the latest research progress on the growth endocrine control axis of bony fish, including the latest research results of related in vivo models obtained through genetic manipulation technology, and through these latest research abstracts, new understandings and new challenges show the endocrine control of fish growth The current research area of the shaft. Individual growth is the regulatory characteristic of multiple genes, which are jointly affected by various physiological signal pathways in the body, such as energy metabolism and muscle growth. In the main regulatory signal pathways involved in vertebrate growth, the endocrine regulatory axis and its constituent signals play an important role.

　　Growth and endocrine control axes are mainly growth hormone (GH), insulin-like growth factor (IGF), growth hormone releasing hormone (GHRH), pituitary adenylate cyclase activating peptide (PACAP), somatostatin (SST). It includes Inside. Other neuropeptides and neurotransmitters, growth and metabolism balance, growth and reproductive endocrine regulation interaction, etc.

　　The endocrine regulation axis of fish growth and its growth regulation are of great value for growth hormone, upstream hypothalamic hormone, insulin-like growth factor, downstream molecules, etc. Many signaling molecules do more than just promote the growth of tissues in the body. , It also has a metabolic regulation effect on many nutrients. The influence of other endocrine regulation axis in the body on growth regulation axis cannot be ignored.