发酵乳 z-bo 2020-10-07 353

　　Researchers have detected common bacterial metabolites in fermented foods and found that human and ape cells have receptors that can trigger the movement of immune cells. Edible lactic acid bacteria (a type of bacteria that can turn milk into yogurt and cabbage into sirloin cheese) can provide many health benefits, but scientists explain why these bacteria are ingested at the molecular level. I still don't understand these benefits and how they affect the immune system. Now, Staubert and her colleagues have discovered how lactic acid bacteria interact with our bodies. Initially, researchers are studying cell surface proteins called hydroxycarboxylic acid (HCA) receptors. Most animals have only two such receptors, while humans and apes have only three. Researchers discovered that the metabolite D-phenyllactic acid produced by lactic acid bacteria binds tightly to the third HCA receptor and informs the immune system of its existence. The researchers proposed that the third HCA receptor appeared in the common ancestor of humans and great apes, allowing them to eat rotten food, such as fruits picked from the ground.

　　This research has opened up new insights into the evolutionary dynamics between microorganisms and human hosts and paved the way for new research directions to understand the multiple positive effects of edible fermented foods. it is. Author Claudia Staubert said: "We believe that this receptor is likely to mediate certain beneficial anti-inflammatory effects of lactic acid bacteria on the human body. We believe that it can be used as a potential treatment for inflammatory diseases. Drug targets. That’s why."

　　Future research may reveal the details of how D-phenyl lactic acid affects the immune system and whether its metabolites also affect fat cells. .. This is because fat cells also have a third HCA receptor on their surface.