Gut microbiota may help improve the prediction of type 2 diabetes risk

  The composition of the intestinal flora is very complex and varies from person to person. Various factors (including environmental factors, lifestyle, genetic factors and diseases) affect the intestinal ecosystem of beneficial intestinal flora. Recently, in a research report in the international journal CellHost & Microbe, scientists from the Munich Institute of Technology and other institutions found through research that intestinal flora may improve the prediction of the risk of type 2 diabetes in the population. done. This article analyzes the importance of diurnal changes in the gut microbiota associated with type 2 diabetes, and analyzed more than 4,000 people. At the same time, this research is the first in this field for large-scale future humans.

  Dark Haller said that a so-called prospective cohort study is needed to determine whether changes in the gut microbiome are related to the study of multiple diseases in the human body. In these prospective cohort studies, researchers were able to analyze cross-sections of participants, but none of the participants showed signs of disease. Researchers have taken time to retest these participants. Based on this method, researchers can check whether certain observations represent predictions of future disease development. If the specific intestinal flora cannot maintain the circadian rhythm, that is, its number and function will not change over time, it may be a potential predictor of the development of type 2 diabetes. Knowing this will help improve the diagnosis and treatment of type 2 diabetes researchers. These arrhythmia intestinal flora can be used as biomarkers to indicate the development of underlying diseases. Researchers believe these are dangerous signs. After studying using mathematical models, the researchers found that they contain arrhythmia flora. The microbiological risk markers in this study may contribute to the effective diagnosis of diabetes. In this article, the researchers first analyzed the existing independent group data of the German Environmental Health Research Center and used other German cohorts to verify the findings related to diabetes. Researchers say that in addition to intestinal flora and its changes during the day, other factors (such as BMI) can better predict a person's future health.

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  When collecting human fecal samples for research, it may seriously affect the diagnosis of diseases by researchers. Recording these timestamps is a risk indicator of diseases. It also helps to improve. This study shows how changes in the intestinal flora during the day affect other microbial-related diseases (such as Crohn’s disease and intestinal cancer), because changes in biological species have a significant impact on nutrition-related diseases. Future scientists will need to explain in detail how to do it.