糖尿病,HIV,NRTI药物 z-bo 2020-10-08 350

　　In a new study, researchers at the University of Virginia School of Medicine and other institutes found that a set of drugs used to treat HIV and hepatitis B can be used repeatedly to prevent type 2 diabetes. These researchers found that patients taking these drugs had a 33% lower risk of diabetes. They said that it is meaningful to reduce this risk based on how these drugs work. One drug called lamidine can significantly increase insulin sensitivity in human cell samples and mouse models of diabetes.

　　The corresponding author of the article and Dr. Jaya Krishna Ambati, a researcher at the University of Virginia School of Medicine, have the following status. The fact that this protective effect can prevent diabetes increases our confidence in our findings. "

　　diabetes pandemic

　　About 500 million people in the world suffer from diabetes-mainly type 2 diabetes, and this number is expected to increase sharply in the next few years. Diabetes is caused by the heart related to many chronic diseases (including diseases, atherosclerosis, nerve damage, loss of vision and impaired wound healing), which puts a heavy burden on health. Scientists are desperately looking for better ways to prevent and control diabetes to determine whether a drug called nucleoside reverse transcriptase inhibitor (NRTI) is helpful. Ambati et al., 128,861 HIV, we analyzed five targeted -1 Or a database of hepatitis B patients. One of the main databases is the Veterans Health Department, the largest integrated medical system in the United States. The structure of the database is reasonable, and the database was reviewed from 2000 to 2017.

　　These researchers found that patients taking NRTI were less likely to develop diabetes by more than 30%. Based on their analysis, they predicted in clinical trials that these drugs have a 95% chance of reducing the risk of diabetes by 29%. To understand, these researchers studied the effects of lamibutin and two other similar drugs on human cell samples. All three drugs have been shown to be beneficial, and these drugs have also been shown to be beneficial. We concluded that this may help prevent diabetes overall. (Please note that this study found a link between diabetes and luteal diseases previously associated with Alzheimer's disease and luteal degeneration.

　　Ambaty said: The data and this huge protective effect provide evidence that inhibiting estrogen is beneficial to the human body. We hope that the so-called fluorophore inhibitors are effective not only for diabetes, but also for the macula, as well as for degeneration and Alzheimer's disease. These enzyme inhibitors have low toxicity to NRTI. "